TY - JOUR AU - Xie, Dengbing; Wang, Yiqiong; Yang, Bo; Zhang, Songlin TI - Neodymium-Promoted Highly Selective Carbon–Carbon Double Bond Formation of Ketones with Allyl Halides in the Presence of Diethyl Phosphite SN - 0039-7881 SN - 1437-210X PY - 2020 JO - Synthesis JF - Synthesis LA - EN VL - 52 IS - 22 SP - 3446 EP - 3451 ET - 2020/08/12 DA - 2020/10/21 KW - Barbier-type reaction KW - α-regioselective KW - one-pot reaction KW - diethyl phosphite AB - The carbon–carbon double bond formation via neodymium-mediated Barbier-type reaction of ketones and allyl halides in the presence of diethyl phosphite is reported for the first time. The reaction is highly α-regioselective and was conveniently carried out under mild conditions in a one-pot fashion. From a synthetic point of view, a series of conjugated alkenes were obtained in moderate to good yields in this one-pot reaction with feasible reaction conditions. PB - © Georg Thieme Verlag DO - 10.1055/s-0040-1707219 UR - http://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0040-1707219 ER -