TY - JOUR AU - Carrilho, Flair Jose; Paranaguá-Vezozzo, Denise Cerqueira; Chagas, Aline Lopes; Alencar, Regiane Saraiva de Souza Melo; da Fonseca, Leonardo Gomes TI - Epidemiology of Liver Cancer in Latin America: Current and Future Trends SN - 0272-8087 SN - 1098-8971 PY - 2020 JO - Semin Liver Dis JF - Seminars in Liver Disease LA - EN VL - 40 IS - 02 SP - 101 EP - 110 ET - 2019/11/11 DA - 2020/04/30 KW - Latin America KW - demographics KW - hepatocellular carcinoma KW - risk factors AB - Over 38,000 cases of hepatocellular carcinoma (HCC) are estimated to occur in Latin America annually. The region is characterized by sociocultural heterogeneity and economic disparities, which impose barriers in addressing this major health issue. A significant proportion of patients are still diagnosed in the later stages of the disease, although efforts to implement effective screening programs have been reported by referral centers. While viral hepatitis remains the predominant etiology of liver disease among HCC cases in Latin America, a high prevalence of fatty liver disease in the region is a matter of concern, reflecting the current scenario in many Western countries. In addition, other risk factors such as alcohol, aflatoxin, and early-onset HCC in hepatitis B virus infection contribute to the burden of HCC in Latin America. Interventions to increase screening coverage, expand healthcare access, and implement continuing medical training are key challenges to be overcome. PB - Thieme Medical Publishers DO - 10.1055/s-0039-3399561 UR - http://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0039-3399561 ER -