TY - JOUR AU - Yamashiro, Toshiki; Yamada, Koji; Yoshida, Haruka; Tomisaka, Yutaro; Nishi, Takahide; Abe, Takumi TI - Silver-Mediated Intramolecular Friedel–Crafts-Type Cyclizations of 2-Benzyloxy-3-bromoindolines: Synthesis of Isochromeno[3,4-b] indolines and 3-Arylindoles SN - 0936-5214 SN - 1437-2096 PY - 2019 JO - Synlett JF - Synlett LA - EN VL - 30 IS - 20 SP - 2247 EP - 2252 ET - 2019/11/05 DA - 2019/12/02 KW - Friedel–Crafts KW - cyclization KW - isochromeno[3,4-b]indolines KW - deformylative arylation KW - 3-arylindoles KW - silver AB - We disclose a silver-mediated intramolecular Friedel–Crafts-type cyclization of 2-benzyloxy-3-bromoindolines to afford an untapped family of isochromeno[3,4-b]indolines and 3-arylindoles, in which deformylative arylation of 2-(4-methoxybenzyloxy)-3-bromoindolines is reported for the first time. The isochromeno[3,4-b]indolines can be readily transformed into other heterocyclic moieties. PB - © Georg Thieme Verlag DO - 10.1055/s-0039-1690734 UR - http://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0039-1690734 ER -