TY - JOUR AU - Nolff, Mirja C.; Albert, Rebecca; Reese, Sven; Meyer-Lindenberg, Andrea TI - Comparison of Negative Pressure Wound Therapy and Silver-Coated Foam Dressings in Open Wound Treatment in Dogs: A Prospective Controlled Clinical Trial SN - 0932-0814 SN - 2567-6911 PY - 2018 JO - Vet Comp Orthop Traumatol JF - Veterinary and Comparative Orthopaedics and Traumatology LA - EN VL - 31 IS - 04 SP - 229 EP - 238 ET - 2018/06/11 DA - 2018/07/27 KW - negative pressure wound therapy KW - polyurethane foam KW - wound bioburden KW - open wound management KW - wound KW - wound planimetry KW - dog AB - Objectives To evaluate negative pressure wound therapy (NPWT) for treatment of complicated wounds in dogs.Study Type Prospective randomized clinical studyMaterials and Methods Dogs (n = 26) undergoing open-wound treatment were randomly assigned to one of two groups: Group A (n = 13) NPWT; Group B (n = 13) silver-coated foam dressing. Pairs of patients were matched based on wound conformation, localization, and underlying cause and compared in terms of duration of previous treatment, development of wound size (wound planimetry), time to closure, bacterial bio-burden and complications. Wound dressing changes were performed every 3 days during the first 9 days of therapy for both groups. Statistical analysis was performed.Results Pre-treatment signalment and bacterial status were comparable between groups. Total time to closure was significantly (p = 0.018) shorter in Group A (14.2 days) compared with Group B (28.6 days), and wound planimetry on days 3, 6 and 9 showed significant greater reduction in total wound area for Group A at all-time points (p < 0.05). Furthermore, wounds in Group A showed less progression of local infection than did wounds in Group B (p = 0.01).Conclusion NPWT-treated wounds showed faster closure, improved macro-deformation and less local signs of infection. PB - Georg Thieme Verlag KG DO - 10.1055/s-0038-1639579 UR - http://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0038-1639579 ER -