Membrane localization of cyclic nucleotide phosphodiesterase 3 (PDE3). Two N-Terminal Domains are required for the efficient targeting to, and association of, PDE3 with endoplasmic reticulum. [In Process Citation] - Shakur, Y; Takeda, K; Kenan, Y; Yu, ZX; Rena, G; Brandt, D; Houslay, MD; Degerman, E; Ferrans, VJ; Manganiello, VC (J Biol Chem, 2000)