TY - JOUR AU - Kamate, Mahesh; Hattiholi, Virupaxi TI - Neuroimaging in Neonatal Nonketotic Hyperglycinemia SN - 2146-457X SN - 2146-4588 PY - 2017 JF - Journal of Pediatric Epilepsy LA - EN VL - 06 IS - 03 SP - 161 EP - 163 ET - 2017/07/19 DA - 2017/08/08 KW - nonketotic hyperglycinemia KW - magnetic resonance imaging KW - central tegmental tract KW - neonatologist AB - Nonketotic hyperglycinemia is a fatal disorder of glycine metabolism presenting with intractable epilepsy, hypotonia, and developmental delay in infancy. Diagnostic tests,such as cerebrospinal fluid glycine estimation and genetic diagnostic methods, are not widely available in developing countries and hence many cases are missed or wrongly diagnosed. The magnetic resonance imaging features, such as abnormal signal intensity in the dorsal pons, midbrain, central tegmental tract, cerebral peduncle, and posterior limb of the internal capsule indicate an important clue to the possibility of the disease and help in guiding the treating neonatologist. PB - Georg Thieme Verlag KG DO - 10.1055/s-0037-1604293 UR - http://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0037-1604293 ER -