TY - STAND N1 - General Procedure: Catalytic Solvolysis of Amide 6 A flame-dried 5 mL round-bottomed flask equipped with a magnetic stirring bar and a septum cap was charged with amide 6 (0.20 mmol) and Zn(OTf)2 (0.01 mmol, 5 mol% or 0.004 mmol, 2 mol%; 0.02 mmol, 10 mol% or 0.01 mmol, 5 mol% of Cu(OTf)2 were used for the synthesis of 7ac or 7c, respectively) in a glove box under Ar atmosphere. After adding anhydrous MeOH (2.0 mL; 2 mL of EtOH or iPrOH was used for the synthesis of 7ab or 7ac) at rt, the resulting clear solution was stirred for designated period of reaction time at the same temperature. The reaction mixture was concentrated under reduced pressure, and the resulting residue was purified by flash column chromatography to give esters 7. Methyl cinnamate (7a): white solid; yield 29.7 mg (92%). Ethyl cinnamate (7ab): colorless oil; yield 33.5 mg (95%). Isopropyl Cinnamate (7ac): colorless oil; yield 26.9 mg (71%). Methyl 4-[(tert-butoxycarbonyl)amino]benzoate (7b): white solid; yield 41.4 mg (82%). Methyl 4-(methoxymethoxy)benzoate (7c): clorless oil; yield 35.9 mg (91%). Methyl 4-[(tert-butyldimethylsilyl)oxy]benzoate (7d): colorless oil; yield 51.2 mg (96%). tert-Butyl methyl terephthalate (7e): white solid; yield 42.8 mg (91%). Methyl picolinate (7f): colorless oil; yield 26.7 mg (97%). Methyl 4-oxo-4-phenylbutanoate (7g): colorless oil; yield 36.4 mg (95%). (S)-Methyl 2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino) propanoate (7h): white solid; yield 57.6 mg (89%). ER -