TY - JOUR AU - Jung, Eun-Kyung; Pilkington, Lisa I.; Barker, David TI - Synthesis of Benzodioxane and Benzofuran Scaffolds Found in Neolignans via TMS Triflate Mediated Addition to 1,4-Benzo­dioxane Hemiacetals SN - 0039-7881 SN - 1437-210X PY - 2017 JO - Synthesis JF - Synthesis LA - EN VL - 49 IS - 06 SP - 1190 EP - 1205 ET - 2017/01/17 DA - 2017/03/01 KW - lignin KW - 1,4-benzodioxane KW - benzofuran KW - asymmetric synthesis KW - hemiacetal KW - oxonium KW - Mitsunobu reaction AB - This research reports the successful asymmetric synthesis of both a 9-hydroxy-5′-methoxy-1,4-benzodioxane framework and a highly functionalised benzofuran scaffold. Both synthetically desirable structures are the result of a Lewis acid catalysed addition of an aryl nucleophile to 1,4-benzodioxane hemiacetals and offer a route towards the synthesis of a number of naturally occurring neolignans. PB - © Georg Thieme Verlag DO - 10.1055/s-0036-1588939 UR - http://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0036-1588939 ER -