TY - JOUR AU - Yu, Mangfei; Zhang, Qian; Wang, Jia; Huang, Peng; Yan, Pengfei; Zhang, Rui; Dong, Dewen TI - Triflic Anhydride Mediated Ring-Opening/Recyclization Reaction of α-Carbamoyl α-Oximyl Cyclopropanes with DMF: Synthetic Route to 5-Aminoisoxazoles SN - 0039-7881 SN - 1437-210X PY - 2016 JO - Synthesis JF - Synthesis LA - EN VL - 48 IS - 12 SP - 1934 EP - 1938 ET - 2016/05/10 DA - 2016/06/02 KW - cyclization KW - heterocycles KW - isoxazoles KW - ring-opening reaction AB - A facile and efficient synthesis of fully substituted 5-amino­isoxazoles was developed from α-cyclopropyl β-oximyl amides in the presence of triflic anhydride (Tf2O) in DMF under very mild conditions. The process involves sequential ring-opening and intramolecular cyclization reactions. PB - © Georg Thieme Verlag DO - 10.1055/s-0035-1561437 UR - http://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0035-1561437 ER -