TY - JOUR AU - Gholinejad, Mohammad; Hamed, Fatemeh; Nájera, Carmen TI - Gold Nanoparticles Supported on Polyacrylamide Containing a Phosphorus Ligand as an Efficient Heterogeneous Catalyst for Three-Component Synthesis of Propargylamines in Water SN - 0936-5214 SN - 1437-2096 PY - 2016 JO - Synlett JF - Synlett LA - EN VL - 27 IS - 08 SP - 1193 EP - 1201 ET - 2015/12/28 DA - 2016/04/28 KW - gold nanoparticles KW - alkynes KW - propargylamines KW - multicomponent reaction KW - polyacrylamide AB - Gold nanoparticles supported on a polyacrylamide containing a phosphinite ligand have been synthesized and characterized using different techniques such as TEM, SEM, EDX, XPS, and solid UV analyses. The new material was successfully applied as a heterogeneous catalyst for the three-component A3 coupling of amines, aldehydes, and alkynes to give propargylamines. Reactions are performed in neat water at 80 °C with only 0.05 mol% catalyst loading. The heterogeneous catalyst is recyclable during seven consecutive runs with small decrease in activity. PB - © Georg Thieme Verlag DO - 10.1055/s-0035-1561286 UR - http://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0035-1561286 ER -