TY - JOUR AU - Monaco, Mattia R.; Properzi, Roberta; List, Benjamin TI - An Approach to Highly Hindered BINOL Phosphates SN - 0936-5214 SN - 1437-2096 PY - 2016 JO - Synlett JF - Synlett LA - EN VL - 27 IS - 04 SP - 591 EP - 594 ET - 2015/10/20 DA - 2016/02/17 KW - phosphoric acids KW - confined catalysts KW - asymmetric organocatalysis KW - biaryl synthesis KW - aryne coupling reaction AB - The synthesis of 3-3′-substituted BINOL-derived chiral phosphoric acid catalysts is still largely limited by the limitations of current cross-coupling methodologies. For this reason, despite the importance of sterically demanding catalysts in Brønsted acid catalysis, highly hindered congeners are still unprecedented. Exploiting the aryne addition reaction as key step, we report herein the development of a novel synthetic route to access this unexplored class of catalysts. PB - © Georg Thieme Verlag DO - 10.1055/s-0035-1560771 UR - http://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0035-1560771 ER -