TY - JOUR AU - Zhou, Zhen; Li, Dianbin; Zhou, Hua; Lin, Xiaoli; Li, Censing; Tang, Mingfeng; Feng, Zhou; Li, Ming TI - Plants and Their Bioactive Compounds with the Potential to Enhance Mechanisms of Inherited Cardiac Regeneration SN - 0032-0943 SN - 1439-0221 PY - 2015 JO - Planta Med JF - Planta Medica LA - EN VL - 81 IS - 08 SP - 637 EP - 647 ET - 2015/05/27 DA - 2015/06/03 KW - natural plant compounds KW - cardiovascular diseases KW - myocardial regeneration KW - mechanisms of inherited cardiac regeneration KW - cardiovascular diseases KW - cardiogenin AB - This article reviews the current progress and research indications in the application of natural plant compounds with the potential for the treatment of cardiovascular diseases. Our understanding of how to apply natural plant compounds to enhance mechanisms of inherited cardiac regeneration, which is physiologically pertinent to myocyte turnover or minor cardiac repair, for substantial cardiac regeneration to repair pathological heart injuries is discussed. Although significant progress has been made in the application of natural plant compounds for therapy of heart diseases, the understanding or the application of these compounds specifically for enhancing mechanisms of inherited cardiac regeneration for the treatment of cardiovascular diseases is little. Recent recognition of some natural plant compounds that can repair damaged myocardial tissues through enhancing mechanisms of inherited cardiac regeneration has offered an alternative for clinical translation. Application of natural plant compounds, which show the activity of manipulating gene expressions in such a way to enhance mechanisms of inherited cardiac regeneration for cardiac repair, may provide a promising strategy for the reconstruction of damaged cardiac tissues due to cardiovascular diseases. PB - Georg Thieme Verlag KG DO - 10.1055/s-0035-1545946 UR - http://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0035-1545946 ER -