False-negative (1)(2)(3)I-MIBG SPECT is most commonly found in SDHB-related pheochromocytoma or paraganglioma with high frequency to develop metastatic disease - Fonte, J S; Robles, J F; Chen, C C; Reynolds, J; Whatley, M; Ling, A; Mercado-Asis, L B; Adams, K T; Martucci, V; Fojo, T; Pacak, K (Endocr Relat Cancer, 2012)