TY - JOUR AU - Petrovčić, Matija; Alešković, Marija; Mlinarić-Majerski, Kata TI - One-Pot Synthesis of Pyrrolo[1,2-c]quinazolinone Derivatives SN - 0936-5214 SN - 1437-2096 PY - 2014 JO - Synlett JF - Synlett LA - EN VL - 25 IS - 19 SP - 2769 EP - 2772 ET - 2014/10/07 DA - 2014/11/19 KW - pyrrolo[1,2-c]quinazolinones KW - Suzuki coupling KW - palladium catalysis KW - tandem reaction KW - heterocycles AB - A fast and simple one-pot synthesis of pyrrolo[1,2-c]-quinazolinones is reported. The tandem Suzuki coupling of N-Boc-pyrrol-2-yl boronic acid and ortho-substituted aminoaryl halogenides with subsequent cyclization of the third ring yields a variety of pyrroloquinazolinone scaffolds in good to moderate yields. The palladium-catalyzed cross-coupling reaction is applicable to a wide range of substituted aminoaryl halogenides. PB - © Georg Thieme Verlag DO - 10.1055/s-0034-1379183 UR - http://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0034-1379183 ER -