TY - JOUR AU - Liwosz, Timothy W.; Chemler, Sherry R. TI - Copper-Catalyzed Synthesis of N-Aryl and N-Sulfonyl Indoles from 2-Vinyl­anilines with O2 as Terminal Oxidant and TEMPO as Cocatalyst SN - 0936-5214 SN - 1437-2096 PY - 2015 JO - Synlett JF - Synlett LA - EN VL - 26 IS - 03 SP - 335 EP - 339 ET - 2014/08/25 DA - 2015/02/02 KW - copper KW - oxidation KW - indoles KW - oxygen KW - TEMPO AB - A copper-catalyzed intramolecular alkene oxidative ­amination that utilizes TEMPO as cocatalyst and O2 as the terminal oxidant has been developed. The method furnishes N-aryl and N-sulfonyl indoles from N-aryl and N-sulfonyl 2-vinylanilines, ­respectively. Additionally, sequential copper-catalyzed reactions where initial Chan–Lam coupling of 2-vinylanilines with aryl­boronic acids is followed by oxidative amination of the alkene can generate N-aryl indoles in one pot. PB - © Georg Thieme Verlag DO - 10.1055/s-0034-1379015 UR - http://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0034-1379015 ER -