TY - JOUR AU - Danoun, Grégory; Bayarmagnai, Bilguun; Grünberg, Matthias F.; Matheis, Christian; Risto, Eugen; Gooßen, Lukas J. TI - Sandmeyer Trifluoromethylation SN - 0039-7881 SN - 1437-210X PY - 2014 JO - Synthesis JF - Synthesis LA - EN VL - 46 IS - 17 SP - 2283 EP - 2286 ET - 2014/08/01 DA - 2014/08/20 KW - anilines KW - copper KW - Sandmeyer reaction KW - trifluoromethylation KW - diazonium salts AB - A range of benzotrifluorides are conveniently accessible in high yields from widely available (hetero)aromatic amines and the inexpensive trifluoromethylating agent TMSCF3 through a copper-mediated Sandmeyer trifluoromethylation reaction. Two practical procedures are presented. In the first, the diazonium salts are preformed in an extra reaction step, in the second approach the diazotization and the trifluoromethylation are combined into a one-pot procedure. PB - © Georg Thieme Verlag DO - 10.1055/s-0034-1378549 UR - http://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0034-1378549 ER -