TY - JOUR AU - Takaya, Hikaru; Iwaya, Takashi; Ogata, Kazuki; Isozaki, Katsuhiro; Yokoi, Tomoya; Yoshida, Ryota; Yasuda, Nobuhiro; Seike, Hirofumi; Takenaka, Toshio; Nakamura, Masaharu TI - Synthesis, Structure, and Function of PCP Pincer Transition-Metal-Complex-Bound Norvaline Derivatives SN - 0936-5214 SN - 1437-2096 PY - 2013 JO - Synlett JF - Synlett LA - EN VL - 24 IS - 15 SP - 1910 EP - 1914 ET - 2013/08/13 DA - 2013/09/05 KW - amino acids KW - cross-coupling KW - catalysis KW - palladium KW - self-assembly AB - A PCP pincer palladium-complex-bound norvaline, Boc-l-[Pd]Nva-OMe, was synthesized and fully characterized by NMR, FT-ICR-MS, and X-ray crystallography. Selective N- and C-terminus transformations of Boc-l-[Pd]Nva-OMe were performed by conventional deprotection–condensation procedures to afford lipophilic palladium-bound norvaline derivatives without metal detachment. The N-/C-bisfunctionalized palladium-bound norvaline showed self-assembly properties, as evidenced by supramolecular gel formation. The catalytic activity of the supramolecular gel was assessed in the 1,4-conjugate addition of phenylboronic acid. PB - © Georg Thieme Verlag DO - 10.1055/s-0033-1339473 UR - http://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0033-1339473 ER -