TY - JOUR AU - Olszewski, Tomasz K.; Bieniek, Michal; Skowerski, Krzysztof; Grela, Karol TI - A New Tool in the Toolbox: Electron-Withdrawing Group Activated ­Ruthenium Catalysts for Olefin Metathesis SN - 0936-5214 SN - 1437-2096 PY - 2013 JO - Synlett JF - Synlett LA - EN VL - 24 IS - 08 SP - 903 EP - 919 ET - 2013/04/05 DA - 2013/05/03 KW - alkenes KW - metathesis KW - catalysis KW - carbenes KW - ruthenium KW - ­organometallic reagents AB - This account describes the discovery and development of efficient electron-withdrawing group activated Hoveyda–Grubbs catalysts, including a nitro-substituted catalyst and their applications in the syntheses of complex molecules.1 Introduction2 EWG-Activated Hoveyda–Grubbs Complexes2.1 The Discovery and the Story Behind It2.2 The Nitro-Substituted Hoveyda–Grubbs Catalyst2.3 pH-Responsive Catalysts2.4 Fine-Tuning of the EWG Fragment3 Applications of the Nitro-Substituted Hoveyda–Grubbs Catalyst in the Preparation of Compounds of Biological Relevance3.1 Synthesis of BILN 20614 Concluding Remarks PB - © Georg Thieme Verlag DO - 10.1055/s-0032-1318497 UR - http://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0032-1318497 ER -