Rhein, a diacerhein-derived metabolite, modulates the expression of matrix degrading enzymes and the cell proliferation of articular chondrocytes by inhibiting ERK and JNK‐AP‐1 dependent pathways. - Legendre,F.; Bogdanowicz,P.; Martin,G.; Domagala,F.; Leclercq,S.; Pujol,J.P. (Clin Exp Rheumatol, 2007)