Low-density lipoprotein receptor-related protein 5 (LRP5) is essential for normal cholesterol metabolism and glucose-induced insulin secretion. - Fujino,T.; Asaba,H.; Kang,MJ.; Ikeda,Y.; Sone,H.; Takada,S.; Kim,DH.; Ioka,RX.; Ono,M.; Tomoyori,H.; Okubo,M.; Murase,T.; et al. (Proc Natl Acad Sci USA, 2003)