TY - JOUR AU - Al Said, Samer; Ellscheid, Michael; Beltsios, Eleftherios T.; Frey, Norbert TI - Non–Vitamin K Antagonist Oral Anticoagulants in Coronary Artery Disease SN - 0720-9355 SN - 2567-5761 PY - 2021 JO - Hamostaseologie JF - Hämostaseologie LA - DE VL - 42 IS - 03 SP - 201 EP - 209 DA - 2021/10/18 KW - coronary artery disease KW - non–vitamin K antagonist KW - oral anticoagulants KW - direct antithrombin agents KW - atherosclerosis AB - The prevention of atherothrombotic events is the primary goal in the treatment of patients with arteriosclerotic disorders. Despite recent improvements in the management of coronary artery disease (CAD) with revascularization techniques and antiplatelet therapy, some patients remain at risk of recurrent cardiovascular events. This could be related to additional thrombin generation. As a result, there has been interest in developing novel therapies to prevent thromboembolic events, targeting thrombin-mediated pathways. These include non–vitamin K antagonist oral anticoagulants (NOACs). This article aims to summarize the recent clinical studies that investigated the role of NOACs in CAD. PB - Georg Thieme Verlag KG DO - 10.1055/a-1606-7523 UR - http://www.thieme-connect.com/products/ejournals/abstract/10.1055/a-1606-7523 ER -