TY - JOUR AU - Chen, Yi-Zhi; Pan, Jun; Luo, Yuan-Yuan; Jiang, Xi; Zou, Wen-Bin; Qian, Yang-Yang; Zhou, Wei; Liu, Xiao; Li, Zhao-Shen; Liao, Zhuan TI - Detachable string magnetically controlled capsule endoscopy for complete viewing of the esophagus and stomach SN - 0013-726X SN - 1438-8812 PY - 2019 JO - Endoscopy JF - Endoscopy LA - EN VL - 51 IS - 04 SP - 360 EP - 364 ET - 2019/03/01 DA - 2019/03/18 AB - Background Esophageal capsule endoscopy is reported to be insufficiently accurate to replace esophagogastroduodenoscopy (EGD) because the passage of the capsule through the esophagus is passive and precludes a thorough investigation. We developed a modified capsule endoscopy technique, called detachable string magnetically controlled capsule endoscopy (DS-MCE), and performed a pilot study to assess the feasibility and safety of this novel technique.Methods 4 healthy volunteers and 21 patients with suspected esophageal disease first underwent DS-MCE followed by EGD within 1 week. Outcomes included technical success of DS-MCE, adverse events, discomfort, and diagnostic accuracy.Results DS-MCE was successfully carried out in all 25 participants. No adverse events were observed. Mean overall discomfort score during DS-MCE was 0.96 (range 0 – 3). DS-MCE diagnoses were in accordance with EGD in all 25 participants. The per-patient sensitivity of DS-MCE for esophageal disease detection was 100 %. The accuracy of DS-MCE for grading esophageal varices and reflux esophagitis were 66.7 % and 100 %, respectively.Conclusions DS-MCE was a feasible, safe, and well-tolerated method for viewing the esophagus and proceeding with gastric examination after string detachment. PB - © Georg Thieme Verlag KG DO - 10.1055/a-0856-6845 UR - http://www.thieme-connect.com/products/ejournals/abstract/10.1055/a-0856-6845 ER -