TY - JOUR AU - Calabrese, Edward J. TI - Hormesis within a mechanistic context SN - 1475-4916 SN - 1476-4245 PY - 2015 JO - Homeopathy JF - Homeopathy LA - EN VL - 104 IS - 02 SP - 90 EP - 96 DA - 2017/12/19 KW - Hormesis KW - Dose–response KW - Biphasic KW - U-shaped KW - Adaptive response AB - This paper provides an assessment of the mechanistic foundations of hormesis and how such understandings evolved over the course of the past century. Particular emphasis is placed on recent developments particularly with respect to receptor-based and cell signaling-based pathways. Of particular importance is that the quantitative feature of the hormetic dose response are independent of mechanism. PB - Georg Thieme Verlag KG DO - 10.1016/j.homp.2015.01.002 UR - http://www.thieme-connect.com/products/ejournals/abstract/10.1016/j.homp.2015.01.002 ER -