Thromb Haemost 2005; 94(06): 1118-1119
DOI: 10.1160/TH05-11-0712
Editorial Focus
Schattauer GmbH

Epithelium, heal thyself !

Mitchell A. Olman
1   Department of Medicine and Division of Pulmonary and Critical Care Medicine at the University of Alabama, Birmingham, Alabama, USA
› Author Affiliations
Further Information

Publication History

Received 02 November 2005

Accepted 03 November 2005

Publication Date:
07 December 2017 (online)

 

 
  • References

  • 1 Olman MA. Perspective on epithelial cell modulation of airway fibrosis in asthma. Am J Respir Cell Mol Biol 2003; 28: 125-8.
  • 2 Olman MA. The fibroproliferative phase of acute lung injury. In: Acute Respiratory Distress Syndrome. Matthay M, Lenfant C. editors 2003: 313-54.
  • 3 Kalluri R, Neilson EG. Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest 2003; 112: 1776-84.
  • 4 Van Leer C, Stutz M, Haeberli A. et al Urokinase plasminogen activator released from alveolar epithelial cells modulates alveolar epithelial repair in vitro . Thromb Haemost 2005; 94: 1257-64.
  • 5 Olman MA, White KE, Ware L. et al Acute lung injury edema fluid mediates fibroblast proliferation and gene expression through interleukin-1. J Immunol 2004; 172: 2668-77.
  • 6 Lazrak A, Samanta A, Matalon S. Biophysical properties and molecular characterization of amiloride-sensitive sodium channels in A549 cells. Am J Physiol Lung Cell Mol Physiol 2000; 278: L838-L857.
  • 7 Olman MA. t-PA and PAI-1 in lung injury and repair. In: Encyclopedia of Respiratory Medicine. Laurent G. editor. Elsevier; Oxford, UK: 2005
  • 8 Cho SH, Tam SW, Demissie-Sanders S. et al Production of plasminogen activator inhibitor-1 by human mast cells and its possible role in asthma. J Immunol 2000; 165: 3154-61.
  • 9 Eitzman DT, McCoy RD, Zheng X. et al Bleomycin-induced pulmonary fibrosis in transgenic mice that either lack or overexpress the murine plasminogen activator inhibitor-1 gene. J Clin Invest 1996; 1: 232-7.
  • 10 Olman MA, Simmons WL, Pollman DJ. et al Polymerization of fibrinogen in murine bleomycin-induced lung injury. Am J Physiol 1996; 271: L519-L526.
  • 11 Hattori N, Degen JL, Sisson TH. et al Bleomycininduced pulmonary fibrosis in fibrinogen-null mice. J Clin Invest 2000; 106: 1341-50.
  • 12 Ploplis VA, Wilberding JA, McLennan L. et al A total fibrinogen deficiency is compatible with the development of pulmonary fibrosis in mice. Am J Pathol 2000; 157: 703-8.
  • 13 Hattori N, Mizuno S, Yoshida Y. et al The plasminogen activation system reduces fibrosis in the lung by a hepatocyte growth factor-dependent mechanism. Am J Pathol 2004; 164: 1091-8.
  • 14 Sheppard D. Functions of pulmonary epithelial integrins: from development to disease. Physiol Rev 2003; 83: 9673-86.
  • 15 Kim HJ, Ingbar DH, Henke CA. Integrin mediation of type II cell adherence to provisional matrix proteins. Am J Physiol 1996; 271: L277-L286.
  • 16 Kim HJ, Henke CA, Savik SK. et al Integrin mediation of alveolar epithelial cell migration on fibronectin and type I collagen. Am J Physiol 1997; 273: L134-L141.
  • 17 Simpson-Haidaris PJ. Induction of fibrinogen biosynthesis and secertion from cultured pulmonary epithelial cells. Blood 1997; 89: 873-82.
  • 18 Simpson-Haidaris PJ, Courtney MA, Wright TW. et al Induction of fibrinogen expression in the lung epithelium during Pneainocystis carinil pneumonia. Infect Immun 1998; 66: 4431-9.
  • 19 Odrijin TM, Haidaris CG, Lerner NB. et al Integrin αvβ3-mediated endocytosis of immobilized fibrinogen by A549 lung alveolar epithelial cells. Am J Respir Cell Mol Biol 2001; 24: 12-21.
  • 20 Olman MA, Hagood JS, Simmons WL. et al Fibrin fragment induction of plasminogen activator inhibitor transcription is mediated by activator protein-1 through a highly conserved element. Blood 1999; 94: 2029-38.
  • 21 Gross TJ, Simon RH, Sitrin RG. Expression of urokinase-type plasminogen activator by rat pulmonary alveolar epithelial cells. Am J Respir Cell Mol Biol 1990; 3: 449-56.
  • 22 Marshall BC, Sageser DS, Rao NV. et al Alveolar epithelial cell plasminogen activator. Characterization and regulation. J Biol Chem 1990; 265: 8198-204.
  • 23 Haxegawn T, Sorensen L, Dom M. et al Induction of urokinase-type plasminogen activator receptor by IL-1B. Am J Respir Cell Mol Biol 1997; 16: 683-92.