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Synfacts 2008(8): 0790-0790  
DOI: 10.1055/s-2008-1077897
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis of ent-Cholesterol

Contributor(s): Philip Kocienski, Arndt W. Schmidt
J. D. Belani, S. D. Rychnovsky*
University of California, Irvine, USA
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Publication History

Publication Date:
23 July 2008 (online)

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Significance

A scalable access to ent-cholesterol is reported. Since steroids occur in nature only as a single enantiomer, chemical synthesis of their ‘unnatural’ counterparts is required for biological studies.