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Planta Med 1980; 40(12): 320-327
DOI: 10.1055/s-2008-1074978
DOI: 10.1055/s-2008-1074978
Research Articles
© Georg Thieme Verlag Stuttgart · New York
Purification and Separation of Digoxin by Removal of Accompanying Glycosides as Phenylboronate Derivatives
Further Information
Publication History
Publication Date:
29 April 2008 (online)
Abstract
A new process has been developed for the purification and separation of digoxin from accompanying glycosides, utilizing their common feature of containing 1,3-diol units in their skeletons which can form cyclic esters with phenylboronic acid. As the polarity of the glycoside phenylboronates is substantially different from that of digoxin, they can be separated easily.
Key Word Index
Digitalis lanata - Scrophulariaceae - Digoxin-Purification - Cardenolidephenylboronates.