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Neuropediatrics 2007; 38(6): 287-291
DOI: 10.1055/s-2008-1062705
Original Article

© Georg Thieme Verlag KG Stuttgart · New York

Seizure Semiology of Lesional Frontal Lobe Epilepsies in Children

D. Battaglia 1 , D. Lettori 1 , I. Contaldo 1 , C. Veredice 1 , A. Sacco 1 , J. Vasco 1 , D. Martinelli 1 , D. Chieffo 1 , T. Tartaglione 2 , C. Colosimo 2 , C. Di Rocco 3 , F. Guzzetta 1
  • 1Catholic Uinversity, Child Neurology, Rome, Italy
  • 2Catholic University, Radiology, Rome, Italy
  • 3Catholic University, Child Neurosurgery, Rome, Italy
Further Information

Publication History

received 22.08.2007

accepted 19.01.2008

Publication Date:
06 May 2008 (online)

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Abstract

The aim of the study was to analyse the semiology of seizures in children with frontal lobe epilepsy (FLE) and to compare them with other paediatric cohorts described in the literature as well as with adult counterparts. We analysed 174 registered seizures of 18 cases under 12 years with lesional epilepsy whose frontal origin was defined by the concordance of neuroimaging and ictal electrographic findings, and confirmed by surgery in the six cases operated on. Seizures were generally short, with a high daily frequency and usually related to sleep. The most characteristic semiological pattern consisted of complex motor seizures, particularly hypermotor. Often seizures corresponded to a mixture of different semiological patterns (tonic, gelastic, automotor, hypermotor, versive) presenting in the same seizure, often as a unique type in the same patient. With regard to several aspects the semiology of FLE in our cohort looks like that reported in adult series, in particular as to the frequency of complex motor seizures. However, our cohort was also characterised by a more protean array of seizure semiology, stressing the occurrence of seizures typically present in adults (versive and complex motor) and of some seizure patterns more characteristic in children such as epileptic spasms; moreover, the rare occurrence of secondarily generalised tonic clonic seizures (SGTCS) was confirmed.

Key words

frontal lobe epilepsy - seizure semiology - childhood

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Correspondence

F. Guzzetta

Francesco Guzzetta

Catholic University

Child Neurology

Largo Gemelli 8

00168 Rome

Italy

Email: fguzzetta@rm.unicatt.it

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