Synfacts 2008(4): 0429-0429  
DOI: 10.1055/s-2008-1042779
Polymer-Supported Synthesis
© Georg Thieme Verlag Stuttgart · New York

Preparation of Peptoids with Ligands

Contributor(s): Yasuhiro Uozumi, Yoichi M. A. Yamada
G. Maayan, B. Yoo, K. Kirshenbaum*
New York University, USA
Further Information

Publication History

Publication Date:
19 March 2008 (online)

Significance

The solid-phase preparation of peptoids with terpyridine, phenanthroline, and hydroxyquinoline groups was described. Thus, N-substituted glycine trimers 7, tetramer 8, and pentamers 9 were given in 56 to >95% purity (8 examples) by employing a solid-phase synthesis protocol from Rink amide resin 1.