Moyamoya Disease in Three Siblings - Follow-Up Study with Magnetic Resonance Angiography (MRA)

M. Kikuchi; H. Hayakawa; I. Takahashi; K. Nagao; H. Hoshino; S. Kudo; K. Ito

doi:10.1055/s-2007-979716

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Neuropediatrics 1995; 26(1): 33-36
DOI: 10.1055/s-2007-979716

Short communications

Moyamoya Disease in Three Siblings - Follow-Up Study with Magnetic Resonance Angiography (MRA)

M. Kikuchi¹ , H. Hayakawa¹ , I. Takahashi¹ , K. Nagao¹ , H. Hoshino¹ , S. Kudo² , K. Ito²

¹Department of Pediatrics, Hitachi General Hospital, Hitachi, Ibaraki, 317, Japan
²Neurosurgery, Hitachi General Hospital, Hitachi, Ibaraki, 317, Japan

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Publication History

Publication Date:
19 April 2007 (online)

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Abstract

Three siblings with moyamoya disease including identical twins are reported. Although the younger of identical twins had no neurological problems, CT and MRI detected cerebral infarctions and cerebral angiography showed the typical features of moyamoya disease. All three cases underwent encephalo-duro-arterio-synangiosis (EDAS), and serial magnetic resonance angiography (MRA) showed that the distal portions of the middle cerebral artery (MCA) were well perfused through surgically created anastomoses. There were no findings of disease progression. MRA might play an important role in follow-up studies of moyamoya disease.

Key words

Moyamoya disease - Familial occurrence - MR angiography

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