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Synfacts 2007(8): 0793-0793  
DOI: 10.1055/s-2007-968715
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York

Synthesis of (±)-Marcfortine B

Contributor(s): Philip Kocienski, Fiona Black
B. M. Trost*, N. Cramer, H. Bernsmann
Stanford University, USA
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Publication History

Publication Date:
24 July 2007 (online)

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Significance

Marcfortine B is a secondary metabolite isolated from several Penicillium species. A trimethylenemethane [3+2] cycloaddition and a radical cyclization are used to construct two of the seven rings.