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Horm Metab Res 1981; 13(7): 394-395
DOI: 10.1055/s-2007-1019279
DOI: 10.1055/s-2007-1019279
Partition of Thyroid Hormone among Erythrocyte Cytosol, Erythrocyte Membrane and Human Plasma Binding Sites
Further Information
Publication History
1980
1980
Publication Date:
14 March 2008 (online)
Summary
The partition of thyroid hormone among binding sites on plasma proteins, erythrocyte (RBC) membranes and cytoplasmic proteins has been examined in the context of recent direct estimates of intracellular RBC thyroid hormone content. Isotopic T3 and T4 uptakes by washed RBCs are identical (> 80 % of tracer at 4 hr), but RBC binding when RBCs are suspended in plasma favors T3 (10 % uptake vs. 2.5 % for T4). The RBC cytosol : plasma T3 ratio is 1 : 21.
Key-Words:
Thyroxine - Triiodothyronine - Plasma Proteins - Cytoplasm