Anti-Inflammatory Activity of Acetophenones from Ophryosporus axilliflorus

Laura Favier; Carlos Tonn; Eduardo Guerreiro; Alejandra Rotelli; Lilian Pelzer

doi:10.1055/s-2006-957543

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Planta Med 1998; 64(7): 657-659
DOI: 10.1055/s-2006-957543

Letter

Anti-Inflammatory Activity of Acetophenones from Ophryosporus axilliflorus

Laura Favier¹ , Carlos Tonn¹ , Eduardo Guerreiro¹ , Alejandra Rotelli² , Lilian Pelzer²

¹INTEQUI-CONICET Universidad Nacional de San Luis, Chacabuco y Pedernera, San Luis, Argentina
²Cátedra de Farmacología, Facultad de Química, Bioquímica y Farmacia, Universidad Nacional de San Luis, Chacabuco y Pedernera, San Luis, Argentina

Further Information

Publication History

1997

1998

Publication Date:
04 January 2007 (online)

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Abstract

Seven acetophenone derivatives were isolated from the aerial parts of Ophryosporus axilliflorus (Griseb.) Hieron. These compounds were subjected to the carrageenan-induced mouse paw edema test where tremetone (7) showed extremely anti-inflammatory activity. Furthermore, the non-benzofuran acetophenones 5 and 6, showed a significant response.

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