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Aktuelle Ernährungsmedizin 2007; 32: S93-S96
DOI: 10.1055/s-2006-951890
Leitlinie Parenterale Ernährung der DGEM
© Georg Thieme Verlag KG Stuttgart · New York

15 Gastroenterologie

R.-J.  Schulz (AG-Leiter), S.  C.  Bischoff, B.  Koletzko
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Publication History

Publication Date:
04 March 2008 (online)

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Schlüsselwörter

chronisch entzündliche Darmerkrankungen - Morbus Crohn - Colitis ulcerosa - Pankreatitis

Key words

parenteral nutrition - inflammatory bowel disease - Crohn's disease - ulcerative colitis - pancreatitis

  • 1 Buchman A L, Scolapio J, Fryer J. AGA technical review on short bowel syndrome and intestinal transplantation.  Gastroenterol. 2003;  124 1111-1134
    PubMedGoogle Scholar
  • 2 Bartels M, Nagel E, Pichlmayr R. What is the role of nutrition in ulcerative colitis? A contribution to the current status of diet therapy in treatment of inflammatory bowel diseases.  Langenbecks Arch Chir. 1995;  380 4-11
    PubMedGoogle Scholar
  • 3 Diamanti A, Gambarara M, Knafelz D. et al . Prevalence of liver complications in pediatric patients on home parenteral nutrition: indications for intestinal or combined liver-intestinal transplantation.  Transplant Proc. 2003;  35 3047-3049
    CrossrefPubMedGoogle Scholar
  • 4 Iyer K R, Srinath C, Horslen S. et al . Late graft loss and long-term outcome after isolated intestinal transplantation in children.  J Pediatr Surg. 2002;  37 151-154
    CrossrefPubMedGoogle Scholar
  • 5 Keller K M, Wirth S. Parenteral nutrition in treatment of short stature in adolescents with Crohn disease.  Klin Pädiatr. 1992;  204 411-416
    PubMedGoogle Scholar
  • 6 Kelly D G, Fleming C R. Nutritional considerations in inflammatory bowel diseases.  Gastroenterol Clin North Am. 1995;  24 597-611
    PubMedGoogle Scholar
  • 7 Kolb S. Parenterale Ernährung zu Hause bei Morbus Crohn.  Ernährung. 1990;  1 40-44
    PubMedGoogle Scholar
  • 8 Ruemmele F M, Roy C C, Levy E, Seidman E G. Nutrition as primary therapy in pediatric Crohn's disease: fact or fantasy?.  J Pediatr. 2000;  136 285-291
    CrossrefPubMedGoogle Scholar
  • 9 Silk D B. Medical management of severe inflammatory disease of the rectum: nutritional aspects.  Baillieres Clin Gastroenterol. 1992;  6 27-41
    CrossrefPubMedGoogle Scholar
  • 10 Stokes M A. Crohn's disease and nutrition.  Br J Surg. 1992;  79 391-394
    CrossrefPubMedGoogle Scholar
  • 11 Greenberg G R, Fleming C R, Jeejeebhoy K N, Rosenberg I H, Sales D, Tremaine W J. Controlled trial of bowel rest and nutritional support in the management of Crohn's disease.  Gut. 1988;  29 1309-1315
    CrossrefPubMedGoogle Scholar
  • 12 Gonzalez-Huix F, Fernandez-Banares F, Esteve-Comas M. et al . Enteral versus parenteral nutrition as adjunct therapy in acute ulcerative colitis.  Am J Gastroenterol. 1993;  88 227-232
    PubMedGoogle Scholar
  • 13 Gilroy R, Sudan D. Liver and small bowel transplantation: therapeutic alternatives for the treatment of liver disease and intestinal failure.  Semin Liver Dis. 2000;  20 437-450
    Article in Thieme ConnectPubMedGoogle Scholar
  • 14 Goh J, O'Morain C A. Review article: nutrition and adult inflammatory bowel disease.  Aliment Pharmacol Ther. 2003;  17 307-320
    CrossrefPubMedGoogle Scholar
  • 15 Sax H C, Warner B W, Talamini M A. et al . Early total parenteral nutrition in acute pancreatitis: lack of beneficial effects.  Am J Surg. 1987;  153 117-124
    CrossrefPubMedGoogle Scholar
  • 16 Tsujikawa T, Andoh A, Fujiyama Y. Enteral and parenteral nutrition therapy for Crohn's disease.  Curr Pharm Des. 2003;  9 323-332
    CrossrefPubMedGoogle Scholar
  • 17 Evans J P, Steinhart A H, Cohen Z, McLeod R S. Home total parenteral nutrition: an alternative to early surgery for complicated inflammatory bowel disease.  J Gastrointest Surg. 2003;  7 562-566
    CrossrefPubMedGoogle Scholar
  • 18 Abu-Elmagd K, Bond G. Gut failure and abdominal visceral transplantation.  Proc Nutr Soc. 2003;  62 727-737
    CrossrefPubMedGoogle Scholar
  • 19 American Gastroenterological Association . American Gastroenterological Association medical position statement: parenteral nutrition.  Gastroenterology. 2001;  121 966-969
    PubMedGoogle Scholar
  • 20 Campos F G, Waitzberg D L, Teixeira M G, Mucerino D R, Habr-Gama A, Kiss D R. Inflammatory bowel diseases: principles of nutritional therapy.  Rev Hosp Clin Fac Med Sao Paulo. 2002;  57 187-198
    PubMedGoogle Scholar
  • 21 Cucino C, Sonnenberg A. Cause of death in patients with inflammatory bowel disease.  Inflamm Bowel Dis. 2001;  7 250-255
    CrossrefPubMedGoogle Scholar
  • 22 Forbes A. Review article: Crohn's disease - the role of nutritional therapy.  Aliment Pharmacol Ther. 2002;  16, Suppl 4 48-52
    CrossrefPubMedGoogle Scholar
  • 23 Higgens C S, Keighley M R, Allan R N. Impact of preoperative weight loss and body composition changes on postoperative outcome in surgery for inflammatory bowel disease.  Gut. 1984;  25 732-736
    CrossrefPubMedGoogle Scholar
  • 24 Hwang T L, Lue M C, Chen L L. Early use of cyclic TPN prevents further deterioration of liver functions for the TPN patients with impaired liver function.  Hepatogastroenterology. 2000;  47 1347-1350
    PubMedGoogle Scholar
  • 25 Meadows N. Monitoring and complications of parenteral nutrition.  Nutrition. 1998;  14 806-808
    CrossrefPubMedGoogle Scholar
  • 26 Muiesan P, Dhawan A, Novelli M, Mieli-Vergani G, Rela M, Heaton N D. Isolated liver transplant and sequential small bowel transplantation for intestinal failure and related liver disease in children.  Transplantation. 2000;  69 2323-2326
    PubMedGoogle Scholar
  • 27 Müller A, Neuhaus P. Dünndarmtransplantation - klinischer Stand und eigene Ergebnisse.  Dtsch Ärztebl. 2004;  101 38-43
    PubMedGoogle Scholar
  • 28 Seo M, Okada M, Yao T, Furukawa H, Matake H. The role of total parenteral nutrition in the management of patients with acute attacks of inflammatory bowel disease.  J Clin Gastroenterol. 1999;  29 270-275
    CrossrefPubMedGoogle Scholar
  • 29 Stange E, Schreiber S, Raedler A. Therapie des Morbus Crohn - Ergebnisse einer Konsensuskonferenz der Deutschen Gesellschaft für Verdauungs- und Stoffwechselerkrankungen.  Z Gastroenterol. 1997;  35 541-554
    PubMedGoogle Scholar
  • 30 Lowen C C, Greene L M, McClave S A. Nutritional support in patients with inflammatory bowel disease.  Postgrad Med. 1992;  91 407-414
    PubMedGoogle Scholar
  • 31 Pupelis G, Selga G, Austrums E, Kaminski A. Jejunal feeding, even when instituted late, improves outcomes in patients with severe pancreatitis and peritonitis.  Nutrition. 2001;  17 91-94
    CrossrefPubMedGoogle Scholar
  • 32 Bodoky G, Harsanyi L, Pap A, Tihanyi T, Flautner L. Effect of enteral nutrition on exocrine pancreatic function.  Am J Surg. 1991;  161 144-148
    CrossrefPubMedGoogle Scholar
  • 33 Abou-Assi S, Craig K, O'Keefe S J. Hypocaloric jejunal feeding is better than total parenteral nutrition in acute pancreatitis: results of a randomized comparative study.  Am J Gastroenterol. 2002;  97 2255-2262
    CrossrefPubMedGoogle Scholar
  • 34 Gupta R, Patel K, Calder P C, Yaqoob P, Primrose J N, Johnson C D. A randomised clinical trial to assess the effect of total enteral and total parenteral nutritional support on metabolic, inflammatory and oxidative markers in patients with predicted severe acute pancreatitis (APACHE II > or = 6).  Pancreatology. 2003;  3 406-413
    CrossrefPubMedGoogle Scholar
  • 35 Hernandez-Aranda J C, Gallo-Chico B, Ramirez-Barba E J. Nutritional support in severe acute pancreatitis. Controlled clinical trial.  Nutr Hosp. 1996;  11 160-166
    PubMedGoogle Scholar
  • 36 Kalfarentzos F, Kehagias J, Mead N, Kokkinis K, Gogos C A. Enteral nutrition is superior to parenteral nutrition in severe acute pancreatitis: results of a randomized prospective trial.  Br J Surg. 1997;  84 1665-1669
    CrossrefPubMedGoogle Scholar
  • 37 Louie B, Noseworthy T, Hailey D, Gramlich L, Jacobs P, Warnock G. Enteral or Parenteral Nutrition for Severe Pancreatitis: A Health Technology Assessment.  JPEN. 2002;  26 32
    PubMedGoogle Scholar
  • 38 Mans G. Die Ernährungstherapie der akuten Pankreatitis.  Aktuel Ernaehr Med. 1997;  22 276-280
    PubMedGoogle Scholar
  • 39 Nathens A B, Curtis J R, Beale R J. et al . Management of the critically ill patient with severe acute pancreatitis.  Crit Care Med. 2004;  32 2524-2536
    CrossrefPubMedGoogle Scholar
  • 40 Olah A, Pardavi G, Belagyi T, Nagy A, Issekutz A, Mohamed G E. Early nasojejunal feeding in acute pancreatitis is associated with a lower complication rate.  Nutrition. 2002;  18 259-262
    CrossrefPubMedGoogle Scholar
  • 41 Powell J J, Murchison J T, Fearon K C, Ross J A, Siriwardena A K. Randomized controlled trial of the effect of early enteral nutrition on markers of the inflammatory response in predicted severe acute pancreatitis.  Br J Surg. 2000;  87 1375-1381
    CrossrefPubMedGoogle Scholar
  • 42 Windsor A C, Kanwar S, Li A G. et al . Compared with parenteral nutrition, enteral feeding attenuates the acute phase response and improves disease severity in acute pancreatitis.  Gut. 1998;  42 431-435
    CrossrefPubMedGoogle Scholar
  • 43 Zhao G, Wang C Y, Wang F, Xiong J X. Clinical study on nutrition support in patients with severe acute pancreatitis.  World J Gastroenterol. 2003;  9 2105-2108
    PubMedGoogle Scholar
  • 44 Tenner S. Initial management of acute pancreatitis: critical issues during the first 72 hours.  Am J Gastroenterol. 2004;  99 2489-2494
    CrossrefPubMedGoogle Scholar
  • 45 McClave S A, Greene L M, Snider H L. et al . Comparison of the safety of early enteral vs parenteral nutrition in mild acute pancreatitis.  JPEN J Parenter Enteral Nutr. 1997;  21 14-20
    CrossrefPubMedGoogle Scholar
  • 46 Hallay J, Kovacs G, Szatmari K. et al . Early jejunal nutrition and changes in the immunological parameters of patients with acute pancreatitis.  Hepatogastroenterology. 2001;  48 1488-1492
    PubMedGoogle Scholar
  • 47 Harsanyi L, Bodoky G, Pap A. The effect of jejunal nutrition on pancreatic exocrine function.  Acta Chir Hung. 1992;  33 13-21
    PubMedGoogle Scholar
  • 48 Pandey S K, Ahuja V, Joshi Y K, Sharma M P. A randomized trial of oral refeeding compared with jejunal tube refeeding in acute pancreatitis.  Indian J Gastroenterol. 2004;  23 53-55
    PubMedGoogle Scholar
  • 49 Eatock F C, Chong P, Menezes N. et al . A randomized study of early nasogastric versus nasojejunal feeding in severe acute pancreatitis.  Am J Gastroenterol. 2005;  100 432-439
    CrossrefPubMedGoogle Scholar
  • 50 August D. Guidelines for the use of parenteral and enteral nutrition in adult and pediatric patients.  JPEN J Parenter Enteral Nutr. 2002;  26 68SA-70SA
    PubMedGoogle Scholar
  • 51 Heyland D K, MacDonald S, Keefe L, Drover J W. Total parenteral nutrition in the critically ill patient: a meta-analysis.  JAMA. 1998;  280 2013-2019
    CrossrefPubMedGoogle Scholar
  • 52 Kaushik N, O'Keefe S J. Nutritional support in acute pancreatitis.  Curr Gastroenterol Rep. 2004;  6 320-326
    PubMedGoogle Scholar
  • 53 Mallampalli A, McClave S A, Snider H L. Defining tolerance to enteral feeding in the intensive care unit.  Clin Nutr. 2000;  19 213-215
    CrossrefPubMedGoogle Scholar
  • 54 Jabbar A, Chang W K, Dryden G W, McClave S A. Gut immunology and the differential response to feeding and starvation.  Nutr Clin Pract. 2003;  18 461-482
    CrossrefPubMedGoogle Scholar
  • 55 Marik P E, Zaloga G P. Meta-analysis of parenteral nutrition versus enteral nutrition in patients with acute pancreatitis.  BMJ. 2004;  328 1407
    CrossrefPubMedGoogle Scholar
  • 56 Lasztity N, Hamvas J, Biro L. et al . Effect of enterally administered n-3 polyunsaturated fatty acids in acute pancreatitis - a prospective randomized clinical trial.  Clin Nutr. 2005;  24 198-205
    CrossrefPubMedGoogle Scholar
  • 57 Olah A, Belagyi T, Issekutz A, Gamal M E, Bengmark S. Randomized clinical trial of specific lactobacillus and fibre supplement to early enteral nutrition in patients with acute pancreatitis.  Br J Surg. 2002;  89 1103-1107
    CrossrefPubMedGoogle Scholar
  • 58 Wu H, Wu Z, Wu G. Effect of intralipid on patients with acute necrotic pancreatitis: a prospective clinical study.  Zhonghua Wai Ke Za Zhi. 1995;  33 261-264
    PubMedGoogle Scholar
  • 59 Martinez J, Castilla M, Velasco P. et al . Non-Glucose carbohydrates in the Parenteral Nutrition of Patients with a Systemic Inflammatory Response Syndrome.  Nutricion Hospitalaria. 1999;  14 41
    PubMedGoogle Scholar
  • 60 Beaux A C de, O'Riordain M G, Ross J A, Jodozi L, Carter D C, Fearon K C. Glutamine-supplemented total parenteral nutrition reduces blood mononuclear cell interleukin-8 release in severe acute pancreatitis.  Nutrition. 1998;  14 261-265
    CrossrefPubMedGoogle Scholar
  • 61 Ockenga J, Borchert K, Rifai K, Manns M P, Bischoff S C. Effect of glutamine-enriched total parenteral nutrition in patients with acute pancreatitis.  Clin Nutr. 2002;  21 409-416
    CrossrefPubMedGoogle Scholar
  • 62 Xian H, Qing-Jiu M, Jian-Guo L, Yan-Kui C, Xi-Lin D. Effect of total parenteral nutrition (TPN) with and without glutamine dipeptide supplementation on outcome in severe acute pancreatitis (SAP).  Clin Nutr Suppl. 2004;  1 43-47
    PubMedGoogle Scholar
  • 63 Al Omran M, Groof A, Wilke D. Enteral versus parenteral nutrition for acute pancreatitis. Cochrane Database Syst Rev 2003 CD002837
    Google Scholar
  • 64 Meier R, Beglinger C, Layer P. et al . ESPEN guidelines on nutrition in acute pancreatitis. European Society of Parenteral and Enteral Nutrition.  Clin Nutr. 2002;  21 173-183
    PubMedGoogle Scholar
  • 65 Sun B, Gao Y, Xu J. et al . Role of individually staged nutritional support in the management of severe acute pancreatitis.  Hepatobiliary Pancreat Dis Int. 2004;  3 458-463
    PubMedGoogle Scholar
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