‘In situ’ Generated ‘HCl’ - An Efficient Catalyst for Solvent-Free Hantzsch Reaction at Room Temperature: Synthesis of New Dihydropyridine Glycoconjugates [1]

Abstract

HCl, generated in situ from 2,4,6-trichloro[1,3,5]triazine (TCT, cyanuric chloride), catalyzed a solvent free Hantzsch reaction at room temperature with enhanced reaction rates. The reaction conditions allow facile preparation of glycoconjugates of dihydropyridines under mild reaction conditions in high yields.

Key words

dihydropyridines - glycoconjugates - Hantzsch reaction - 2,4,6-trichloro[1,3,5]triazine (TCT - cyanuric chloride)

1

IICT Communication No. 041117.

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1

IICT Communication No. 041117.