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49.4 591.36 497.28 -0.36 re
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49.4 524.76 497.28 -0.36 re
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49.4 375.12 497.28 -0.36 re
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BT
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BT
7.0003 0 0 7.0003 469.5173 720.4197 Tm
(NsN)Tj
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(R)Tj
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ET
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f
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f
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f
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f
BT
7.0003 0 0 7.0003 393.4145 753.9711 Tm
(Cs)Tj
5.2502 0 0 5.2502 401.97 752.6584 Tm
(2)Tj
7.0003 0 0 7.0003 404.8899 753.9711 Tm
(CO)Tj
5.2502 0 0 5.2502 415.3903 752.6584 Tm
(3)Tj
7.0003 0 0 7.0003 418.3102 753.9711 Tm
(, )Tj
/TT10 1 Tf
0.5557 0 TD
(n)Tj
/TT8 1 Tf
0.5562 0 TD
(-Bu)Tj
5.2502 0 0 5.2502 436.9868 752.6584 Tm
(4)Tj
7.0003 0 0 7.0003 439.9067 753.9711 Tm
(NI)Tj
ET
/Cs5 CS 0.161 0.145 0.149 SC
0 J 0 j 0.48 w 4 M []0 d
489.831 700.02 m
489.868 715.77 l
S
489.818 694.769 m
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f
494.681 694.62 m
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S
494.668 689.369 m
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494.127 694.621 493.602 694.867 493.247 695.293 c
f
BT
7.0003 0 0 7.0003 398.1646 738.9705 Tm
(CH)Tj
5.2502 0 0 5.2502 408.2754 737.6579 Tm
(3)Tj
7.0003 0 0 7.0003 411.1953 738.9705 Tm
(CN, 60 C)Tj
-1.8615 -1.3143 TD
( \(0.1 M\) 85%)Tj
9.1714 -6.9 TD
(Lipogrammistin A)Tj
5.4214 3.3786 TD
(2 steps)Tj
ET
450.015 748.971 m
390.264 748.971 l
S
455.267 748.971 m
449.346 750.406 l
449.77 750.05 450.015 749.525 450.015 748.971 c
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f
1 1 1 sc
304.28 662.28 203.04 -61.92 re
f
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f
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f
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f
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f
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f
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f
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f
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f
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f
0.275 0.275 0.275 sc
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f
0.294 0.294 0.294 sc
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f
0.322 0.322 0.322 sc
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f
0.349 0.349 0.349 sc
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f
0.369 0.369 0.369 sc
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f
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f
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f
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f
0.459 0.459 0.459 sc
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f
0.482 0.482 0.482 sc
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f
0.506 0.506 0.506 sc
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f
0.525 0.525 0.525 sc
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f
0.549 0.549 0.549 sc
311.94 645.2 m
314.832 645.2 317.18 642.852 317.18 639.96 c
317.18 637.068 314.832 634.72 311.94 634.72 c
309.048 634.72 306.7 637.068 306.7 639.96 c
306.7 642.852 309.048 645.2 311.94 645.2 c
f
0.569 0.569 0.569 sc
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314.717 645.219 317.019 642.917 317.019 640.08 c
317.019 637.243 314.717 634.941 311.88 634.941 c
309.043 634.941 306.741 637.243 306.741 640.08 c
306.741 642.917 309.043 645.219 311.88 645.219 c
f
0.584 0.584 0.584 sc
311.82 645.179 m
314.602 645.179 316.859 642.922 316.859 640.14 c
316.859 637.359 314.602 635.101 311.82 635.101 c
309.039 635.101 306.781 637.359 306.781 640.14 c
306.781 642.922 309.039 645.179 311.82 645.179 c
f
0.604 0.604 0.604 sc
311.82 645.198 m
314.546 645.198 316.758 642.986 316.758 640.26 c
316.758 637.534 314.546 635.322 311.82 635.322 c
309.094 635.322 306.882 637.534 306.882 640.26 c
306.882 642.986 309.094 645.198 311.82 645.198 c
f
0.624 0.624 0.624 sc
311.76 645.278 m
314.431 645.278 316.598 643.111 316.598 640.44 c
316.598 637.769 314.431 635.602 311.76 635.602 c
309.089 635.602 306.922 637.769 306.922 640.44 c
306.922 643.111 309.089 645.278 311.76 645.278 c
f
0.643 0.643 0.643 sc
311.64 645.297 m
314.255 645.297 316.378 643.175 316.378 640.56 c
316.378 637.945 314.255 635.823 311.64 635.823 c
309.025 635.823 306.903 637.945 306.903 640.56 c
306.903 643.175 309.025 645.297 311.64 645.297 c
f
0.663 0.663 0.663 sc
311.64 645.257 m
314.2 645.257 316.277 643.18 316.277 640.62 c
316.277 638.06 314.2 635.983 311.64 635.983 c
309.08 635.983 307.003 638.06 307.003 640.62 c
307.003 643.18 309.08 645.257 311.64 645.257 c
f
0.678 0.678 0.678 sc
311.58 645.277 m
314.084 645.277 316.117 643.244 316.117 640.74 c
316.117 638.236 314.084 636.203 311.58 636.203 c
309.076 636.203 307.044 638.236 307.044 640.74 c
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f
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BT
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(Cl)Tj
ET
336.013 645.634 m
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f
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438.784 640.429 440.771 642.416 443.22 642.416 c
f
0.714 0.714 0.714 sc
443.22 642.436 m
445.613 642.436 447.556 640.493 447.556 638.1 c
447.556 635.707 445.613 633.765 443.22 633.765 c
440.827 633.765 438.885 635.707 438.885 638.1 c
438.885 640.493 440.827 642.436 443.22 642.436 c
f
0.729 0.729 0.729 sc
443.16 642.395 m
445.498 642.395 447.395 640.498 447.395 638.16 c
447.395 635.822 445.498 633.925 443.16 633.925 c
440.822 633.925 438.925 635.822 438.925 638.16 c
438.925 640.498 440.822 642.395 443.16 642.395 c
f
0.745 0.745 0.745 sc
443.04 642.415 m
445.322 642.415 447.175 640.562 447.175 638.28 c
447.175 635.998 445.322 634.146 443.04 634.146 c
440.758 634.146 438.905 635.998 438.905 638.28 c
438.905 640.562 440.758 642.415 443.04 642.415 c
f
0.761 0.761 0.761 sc
443.04 642.434 m
445.267 642.434 447.074 640.627 447.074 638.4 c
447.074 636.173 445.267 634.366 443.04 634.366 c
440.813 634.366 439.006 636.173 439.006 638.4 c
439.006 640.627 440.813 642.434 443.04 642.434 c
f
0.776 0.776 0.776 sc
442.98 642.454 m
445.151 642.454 446.914 640.691 446.914 638.52 c
446.914 636.349 445.151 634.586 442.98 634.586 c
440.809 634.586 439.046 636.349 439.046 638.52 c
439.046 640.691 440.809 642.454 442.98 642.454 c
f
0.792 0.792 0.792 sc
442.86 642.533 m
444.976 642.533 446.693 640.816 446.693 638.7 c
446.693 636.584 444.976 634.867 442.86 634.867 c
440.744 634.867 439.027 636.584 439.027 638.7 c
439.027 640.816 440.744 642.533 442.86 642.533 c
f
0.804 0.804 0.804 sc
442.86 642.493 m
444.92 642.493 446.593 640.82 446.593 638.76 c
446.593 636.7 444.92 635.027 442.86 635.027 c
440.8 635.027 439.127 636.7 439.127 638.76 c
439.127 640.82 440.8 642.493 442.86 642.493 c
f
0.82 0.82 0.82 sc
442.8 642.512 m
444.805 642.512 446.432 640.885 446.432 638.88 c
446.432 636.875 444.805 635.248 442.8 635.248 c
440.795 635.248 439.168 636.875 439.168 638.88 c
439.168 640.885 440.795 642.512 442.8 642.512 c
f
0.831 0.831 0.831 sc
442.74 642.532 m
444.689 642.532 446.272 640.949 446.272 639 c
446.272 637.051 444.689 635.468 442.74 635.468 c
440.791 635.468 439.208 637.051 439.208 639 c
439.208 640.949 440.791 642.532 442.74 642.532 c
f
0.843 0.843 0.843 sc
442.68 642.551 m
444.574 642.551 446.111 641.014 446.111 639.12 c
446.111 637.226 444.574 635.689 442.68 635.689 c
440.786 635.689 439.249 637.226 439.249 639.12 c
439.249 641.014 440.786 642.551 442.68 642.551 c
f
0.855 0.855 0.855 sc
442.62 642.571 m
444.458 642.571 445.951 641.078 445.951 639.24 c
445.951 637.402 444.458 635.909 442.62 635.909 c
440.782 635.909 439.289 637.402 439.289 639.24 c
439.289 641.078 440.782 642.571 442.62 642.571 c
f
0.867 0.867 0.867 sc
442.56 642.53 m
444.343 642.53 445.79 641.083 445.79 639.3 c
445.79 637.517 444.343 636.07 442.56 636.07 c
440.777 636.07 439.33 637.517 439.33 639.3 c
439.33 641.083 440.777 642.53 442.56 642.53 c
f
0.878 0.878 0.878 sc
442.5 642.55 m
444.228 642.55 445.63 641.148 445.63 639.42 c
445.63 637.693 444.228 636.29 442.5 636.29 c
440.772 636.29 439.37 637.693 439.37 639.42 c
439.37 641.148 440.772 642.55 442.5 642.55 c
f
0.894 0.89 0.894 sc
442.44 642.629 m
444.112 642.629 445.469 641.272 445.469 639.6 c
445.469 637.928 444.112 636.571 442.44 636.571 c
440.768 636.571 439.411 637.928 439.411 639.6 c
439.411 641.272 440.768 642.629 442.44 642.629 c
f
0.902 0.898 0.902 sc
442.38 642.649 m
443.997 642.649 445.309 641.337 445.309 639.72 c
445.309 638.103 443.997 636.791 442.38 636.791 c
440.763 636.791 439.451 638.103 439.451 639.72 c
439.451 641.337 440.763 642.649 442.38 642.649 c
f
0.914 0.914 0.914 sc
442.32 642.668 m
443.881 642.668 445.148 641.401 445.148 639.84 c
445.148 638.279 443.881 637.012 442.32 637.012 c
440.759 637.012 439.492 638.279 439.492 639.84 c
439.492 641.401 440.759 642.668 442.32 642.668 c
f
0.922 0.922 0.922 sc
442.26 642.628 m
443.766 642.628 444.988 641.406 444.988 639.9 c
444.988 638.394 443.766 637.172 442.26 637.172 c
440.754 637.172 439.532 638.394 439.532 639.9 c
439.532 641.406 440.754 642.628 442.26 642.628 c
f
0.929 0.929 0.929 sc
442.26 642.647 m
443.71 642.647 444.887 641.47 444.887 640.02 c
444.887 638.57 443.71 637.393 442.26 637.393 c
440.81 637.393 439.633 638.57 439.633 640.02 c
439.633 641.47 440.81 642.647 442.26 642.647 c
f
0.937 0.937 0.937 sc
442.14 642.667 m
443.535 642.667 444.667 641.535 444.667 640.14 c
444.667 638.745 443.535 637.613 442.14 637.613 c
440.745 637.613 439.613 638.745 439.613 640.14 c
439.613 641.535 440.745 642.667 442.14 642.667 c
f
0.945 0.945 0.945 sc
442.08 642.686 m
443.419 642.686 444.506 641.599 444.506 640.26 c
444.506 638.921 443.419 637.834 442.08 637.834 c
440.741 637.834 439.654 638.921 439.654 640.26 c
439.654 641.599 440.741 642.686 442.08 642.686 c
f
0.953 0.953 0.953 sc
442.08 642.706 m
443.364 642.706 444.406 641.664 444.406 640.38 c
444.406 639.096 443.364 638.054 442.08 638.054 c
440.796 638.054 439.754 639.096 439.754 640.38 c
439.754 641.664 440.796 642.706 442.08 642.706 c
f
0.957 0.957 0.957 sc
441.96 642.665 m
443.188 642.665 444.185 641.668 444.185 640.44 c
444.185 639.212 443.188 638.215 441.96 638.215 c
440.732 638.215 439.735 639.212 439.735 640.44 c
439.735 641.668 440.732 642.665 441.96 642.665 c
f
0.965 0.965 0.965 sc
441.96 642.745 m
443.133 642.745 444.085 641.793 444.085 640.62 c
444.085 639.447 443.133 638.495 441.96 638.495 c
440.787 638.495 439.835 639.447 439.835 640.62 c
439.835 641.793 440.787 642.745 441.96 642.745 c
f
0.969 0.969 0.969 sc
441.9 642.764 m
443.017 642.764 443.924 641.857 443.924 640.74 c
443.924 639.623 443.017 638.716 441.9 638.716 c
440.783 638.716 439.876 639.623 439.876 640.74 c
439.876 641.857 440.783 642.764 441.9 642.764 c
f
0.976 0.976 0.976 sc
441.78 642.784 m
442.842 642.784 443.704 641.922 443.704 640.86 c
443.704 639.798 442.842 638.936 441.78 638.936 c
440.718 638.936 439.856 639.798 439.856 640.86 c
439.856 641.922 440.718 642.784 441.78 642.784 c
f
0.98 0.98 0.98 sc
441.78 642.803 m
442.786 642.803 443.603 641.986 443.603 640.98 c
443.603 639.974 442.786 639.157 441.78 639.157 c
440.774 639.157 439.957 639.974 439.957 640.98 c
439.957 641.986 440.774 642.803 441.78 642.803 c
f
0.984 0.984 0.984 sc
441.72 642.763 m
442.671 642.763 443.443 641.991 443.443 641.04 c
443.443 640.089 442.671 639.317 441.72 639.317 c
440.769 639.317 439.997 640.089 439.997 641.04 c
439.997 641.991 440.769 642.763 441.72 642.763 c
f
0.988 0.988 0.988 sc
441.6 642.782 m
442.495 642.782 443.222 642.055 443.222 641.16 c
443.222 640.265 442.495 639.538 441.6 639.538 c
440.705 639.538 439.978 640.265 439.978 641.16 c
439.978 642.055 440.705 642.782 441.6 642.782 c
f
0.992 0.992 0.992 sc
441.6 642.802 m
442.44 642.802 443.122 642.12 443.122 641.28 c
443.122 640.44 442.44 639.758 441.6 639.758 c
440.76 639.758 440.078 640.44 440.078 641.28 c
440.078 642.12 440.76 642.802 441.6 642.802 c
f
441.54 642.821 m
442.325 642.821 442.961 642.185 442.961 641.4 c
442.961 640.615 442.325 639.979 441.54 639.979 c
440.755 639.979 440.119 640.615 440.119 641.4 c
440.119 642.185 440.755 642.821 441.54 642.821 c
f
0.996 0.996 0.996 sc
441.42 642.901 m
442.149 642.901 442.741 642.309 442.741 641.58 c
442.741 640.851 442.149 640.259 441.42 640.259 c
440.691 640.259 440.099 640.851 440.099 641.58 c
440.099 642.309 440.691 642.901 441.42 642.901 c
f
441.42 642.86 m
442.094 642.86 442.64 642.314 442.64 641.64 c
442.64 640.966 442.094 640.42 441.42 640.42 c
440.746 640.42 440.2 640.966 440.2 641.64 c
440.2 642.314 440.746 642.86 441.42 642.86 c
f
1 1 1 sc
441.36 642.88 m
441.978 642.88 442.48 642.378 442.48 641.76 c
442.48 641.142 441.978 640.64 441.36 640.64 c
440.742 640.64 440.24 641.142 440.24 641.76 c
440.24 642.378 440.742 642.88 441.36 642.88 c
f
441.24 642.899 m
441.803 642.899 442.259 642.443 442.259 641.88 c
442.259 641.317 441.803 640.861 441.24 640.861 c
440.677 640.861 440.221 641.317 440.221 641.88 c
440.221 642.443 440.677 642.899 441.24 642.899 c
f
444.9 641.97 m
448.957 641.97 452.25 638.677 452.25 634.62 c
452.25 630.563 448.957 627.27 444.9 627.27 c
440.843 627.27 437.55 630.563 437.55 634.62 c
437.55 638.677 440.843 641.97 444.9 641.97 c
S
/Cs5 cs 0.161 0.145 0.149 sc
459.717 647.384 m
459.768 647.034 l
459.818 646.634 l
451.267 638.133 l
450.867 638.534 l
f
BT
7.0003 0 0 7.0003 467.6178 638.0835 Tm
(O)Tj
ET
467.568 642.834 m
467.268 642.334 l
459.818 646.634 l
459.768 647.034 l
459.717 647.384 l
f
481.068 647.334 m
481.068 646.684 l
473.518 642.334 l
473.218 642.834 l
f
BT
7.0003 0 0 7.0003 478.2682 656.5342 Tm
(O)Tj
ET
479.668 655.534 0.6 -9.15 re
f
481.868 655.534 0.6 -9.15 re
f
BT
7.0003 0 0 7.0003 489.1186 638.0835 Tm
(N)Tj
ET
488.519 643.034 m
488.219 642.534 l
481.068 646.684 l
481.068 647.334 l
f
BT
7.0003 0 0 7.0003 499.969 644.2337 Tm
(Ar)Tj
ET
498.319 645.034 m
498.619 644.534 l
495.219 642.534 l
494.969 643.034 l
f
BT
7.0003 0 0 7.0003 489.1186 625.733 Tm
(H)Tj
ET
491.419 637.283 0.6 -7.55 re
f
BT
7.0003 0 0 7.0003 353.6135 646.7338 Tm
(ArNH)Tj
5.2502 0 0 5.2502 370.7245 645.4213 Tm
(2)Tj
7.0003 0 0 7.0003 373.6445 646.7338 Tm
(, CO)Tj
5.2502 0 0 5.2502 388.0347 645.4213 Tm
(2)Tj
7.0003 0 0 7.0003 390.9546 646.7338 Tm
(, Cs)Tj
5.2502 0 0 5.2502 403.3999 645.4213 Tm
(2)Tj
7.0003 0 0 7.0003 406.3198 646.7338 Tm
(CO)Tj
5.2502 0 0 5.2502 416.8203 645.4213 Tm
(3)Tj
7.0003 0 0 7.0003 350.2634 633.4833 Tm
(TBAI, DMF, 60 C, 24 h)Tj
ET
0.48 w
427.015 642.334 m
347.863 642.334 l
S
432.266 642.334 m
426.346 643.769 l
426.77 643.413 427.015 642.888 427.015 642.334 c
427.015 641.78 426.77 641.254 426.346 640.898 c
f
BT
7.0003 0 0 7.0003 306.3618 613.0825 Tm
(Ar = Ph, 4-Me-Ph, 2-pyridyl, 4-pyridyl, 3-Acyl-Ph, 4-NO)Tj
5.2502 0 0 5.2502 476.1663 611.77 Tm
(2)Tj
7.0003 0 0 7.0003 479.0862 613.0825 Tm
(-Ph)Tj
-24.674 -1.3143 TD
( 3-NO)Tj
5.2502 0 0 5.2502 338.6458 602.5696 Tm
(2)Tj
7.0003 0 0 7.0003 341.5657 603.8821 Tm
(-Ph, 3,4-diMe-Ph)Tj
ET
1 1 1 sc
304.28 583.68 234 -50.04 re
f
BT
7.0003 0 0 7.0003 339.3625 556.7972 Tm
0.161 0.145 0.149 sc
(Cl)Tj
ET
330.912 566.298 m
330.912 565.598 l
320.012 559.347 l
319.712 559.847 l
f
339.263 561.497 m
338.962 560.997 l
330.912 565.598 l
330.912 566.298 l
f
BT
7.0003 0 0 7.0003 355.0631 568.6976 Tm
[(Cl)-6827.1(COOH)]TJ
ET
398.965 571.498 m
399.315 571.498 l
399.465 571.198 l
393.115 560.147 l
392.915 560.447 l
392.765 560.747 l
f
396.415 571.648 m
396.915 571.348 l
391.865 562.597 l
391.365 562.897 l
f
392.765 582.198 m
392.915 582.498 l
393.115 582.798 l
399.465 571.798 l
399.315 571.498 l
398.965 571.498 l
f
380.364 582.198 m
380.164 582.498 l
380.014 582.798 l
393.115 582.798 l
392.915 582.498 l
392.765 582.198 l
f
381.514 580.548 10.1 -0.6 re
f
374.164 571.498 m
373.814 571.498 l
373.614 571.798 l
380.014 582.798 l
380.164 582.498 l
380.364 582.198 l
f
380.364 560.747 m
380.164 560.447 l
380.014 560.147 l
373.614 571.198 l
373.814 571.498 l
374.164 571.498 l
f
381.764 562.897 m
381.264 562.597 l
376.214 571.348 l
376.714 571.648 l
f
392.765 560.747 m
392.915 560.447 l
393.115 560.147 l
380.014 560.147 l
380.164 560.447 l
380.364 560.747 l
f
362.313 571.198 m
362.313 571.798 l
373.614 571.798 l
373.814 571.498 l
373.614 571.198 l
f
408.865 571.798 m
408.865 571.198 l
399.465 571.198 l
399.315 571.498 l
399.465 571.798 l
f
BT
7.0003 0 0 7.0003 475.6681 555.2971 Tm
(O)Tj
1.5786 2.7286 TD
(O)Tj
6.3429 -5.4643 TD
(Cl)Tj
ET
467.418 564.797 m
467.418 564.097 l
456.517 557.847 l
456.217 558.347 l
f
475.618 560.097 m
475.318 559.547 l
467.418 564.097 l
467.418 564.797 l
f
489.519 564.797 m
489.519 564.097 l
481.618 559.547 l
481.318 560.097 l
f
500.569 558.447 m
500.569 558.097 l
500.269 557.897 l
489.519 564.097 l
489.519 564.797 l
f
488.069 573.398 0.6 -9.6 re
f
490.369 573.398 0.6 -9.6 re
f
500.869 545.497 m
500.569 545.347 l
500.269 545.147 l
500.269 557.897 l
500.569 558.097 l
500.869 557.897 l
f
502.569 556.747 0.6 -10.1 re
f
511.62 539.297 m
511.62 538.596 l
500.269 545.147 l
500.569 545.347 l
500.869 545.497 l
f
522.32 545.497 m
522.62 545.347 l
522.62 544.997 l
511.62 538.596 l
511.62 539.297 l
f
520.22 546.947 m
520.52 546.397 l
511.77 541.347 l
511.47 541.897 l
f
522.32 557.897 m
522.62 558.097 l
522.92 558.247 l
522.92 545.497 l
522.62 545.347 l
522.32 545.497 l
f
511.62 564.097 m
511.62 564.797 l
522.92 558.247 l
522.62 558.097 l
522.32 557.897 l
f
511.47 561.547 m
511.77 562.097 l
520.52 557.047 l
520.22 556.497 l
f
500.869 557.897 m
500.569 558.097 l
500.569 558.447 l
511.62 564.797 l
511.62 564.097 l
f
530.97 540.897 m
530.67 540.346 l
522.62 544.997 l
522.62 545.347 l
522.92 545.497 l
f
BT
7.0003 0 0 7.0003 357.9133 546.2968 Tm
( Cs)Tj
5.2502 0 0 5.2502 372.3035 544.9842 Tm
(2)Tj
7.0003 0 0 7.0003 375.2234 546.2968 Tm
(CO)Tj
5.2502 0 0 5.2502 385.7238 544.9842 Tm
(3)Tj
7.0003 0 0 7.0003 388.6437 546.2968 Tm
(, NMP)Tj
-4.3899 -1.3143 TD
(MW, 200 C, 5 min)Tj
ET
/Cs5 cs 0 0 0 sc
313.08 564.69 m
317.303 564.69 320.73 561.263 320.73 557.04 c
320.73 552.817 317.303 549.39 313.08 549.39 c
308.857 549.39 305.43 552.817 305.43 557.04 c
305.43 561.263 308.857 564.69 313.08 564.69 c
f
0.039 0.039 0.039 sc
313.02 564.706 m
317.185 564.706 320.566 561.325 320.566 557.16 c
320.566 552.995 317.185 549.614 313.02 549.614 c
308.855 549.614 305.474 552.995 305.474 557.16 c
305.474 561.325 308.855 564.706 313.02 564.706 c
f
0.082 0.082 0.082 sc
312.9 564.781 m
317.008 564.781 320.341 561.448 320.341 557.34 c
320.341 553.233 317.008 549.899 312.9 549.899 c
308.793 549.899 305.459 553.233 305.459 557.34 c
305.459 561.448 308.793 564.781 312.9 564.781 c
f
0.118 0.118 0.118 sc
312.9 564.737 m
316.95 564.737 320.237 561.45 320.237 557.4 c
320.237 553.35 316.95 550.063 312.9 550.063 c
308.85 550.063 305.563 553.35 305.563 557.4 c
305.563 561.45 308.85 564.737 312.9 564.737 c
f
0.145 0.145 0.145 sc
312.84 564.752 m
316.832 564.752 320.072 561.512 320.072 557.52 c
320.072 553.528 316.832 550.288 312.84 550.288 c
308.848 550.288 305.608 553.528 305.608 557.52 c
305.608 561.512 308.848 564.752 312.84 564.752 c
f
0.169 0.169 0.169 sc
312.72 564.767 m
316.654 564.767 319.847 561.574 319.847 557.64 c
319.847 553.706 316.654 550.513 312.72 550.513 c
308.786 550.513 305.593 553.706 305.593 557.64 c
305.593 561.574 308.786 564.767 312.72 564.767 c
f
0.196 0.196 0.196 sc
312.72 564.783 m
316.597 564.783 319.743 561.637 319.743 557.76 c
319.743 553.883 316.597 550.737 312.72 550.737 c
308.843 550.737 305.697 553.883 305.697 557.76 c
305.697 561.637 308.843 564.783 312.72 564.783 c
f
0.224 0.224 0.224 sc
312.66 564.798 m
316.479 564.798 319.578 561.699 319.578 557.88 c
319.578 554.061 316.479 550.962 312.66 550.962 c
308.841 550.962 305.742 554.061 305.742 557.88 c
305.742 561.699 308.841 564.798 312.66 564.798 c
f
0.247 0.247 0.247 sc
312.6 564.814 m
316.361 564.814 319.414 561.761 319.414 558 c
319.414 554.239 316.361 551.186 312.6 551.186 c
308.839 551.186 305.786 554.239 305.786 558 c
305.786 561.761 308.839 564.814 312.6 564.814 c
f
0.275 0.275 0.275 sc
312.54 564.829 m
316.243 564.829 319.249 561.823 319.249 558.12 c
319.249 554.417 316.243 551.411 312.54 551.411 c
308.837 551.411 305.831 554.417 305.831 558.12 c
305.831 561.823 308.837 564.829 312.54 564.829 c
f
0.294 0.294 0.294 sc
312.42 564.844 m
316.066 564.844 319.024 561.886 319.024 558.24 c
319.024 554.594 316.066 551.636 312.42 551.636 c
308.774 551.636 305.816 554.594 305.816 558.24 c
305.816 561.886 308.774 564.844 312.42 564.844 c
f
0.322 0.322 0.322 sc
312.42 564.86 m
316.008 564.86 318.92 561.948 318.92 558.36 c
318.92 554.772 316.008 551.86 312.42 551.86 c
308.832 551.86 305.92 554.772 305.92 558.36 c
305.92 561.948 308.832 564.86 312.42 564.86 c
f
0.349 0.349 0.349 sc
312.36 564.875 m
315.89 564.875 318.755 562.01 318.755 558.48 c
318.755 554.95 315.89 552.085 312.36 552.085 c
308.83 552.085 305.965 554.95 305.965 558.48 c
305.965 562.01 308.83 564.875 312.36 564.875 c
f
0.369 0.369 0.369 sc
312.24 564.891 m
315.712 564.891 318.531 562.072 318.531 558.6 c
318.531 555.128 315.712 552.309 312.24 552.309 c
308.768 552.309 305.949 555.128 305.949 558.6 c
305.949 562.072 308.768 564.891 312.24 564.891 c
f
0.392 0.392 0.392 sc
312.24 564.906 m
315.655 564.906 318.426 562.135 318.426 558.72 c
318.426 555.305 315.655 552.534 312.24 552.534 c
308.825 552.534 306.054 555.305 306.054 558.72 c
306.054 562.135 308.825 564.906 312.24 564.906 c
f
0.42 0.42 0.42 sc
312.18 564.921 m
315.537 564.921 318.261 562.197 318.261 558.84 c
318.261 555.483 315.537 552.759 312.18 552.759 c
308.823 552.759 306.099 555.483 306.099 558.84 c
306.099 562.197 308.823 564.921 312.18 564.921 c
f
0.439 0.439 0.439 sc
312.12 564.937 m
315.419 564.937 318.097 562.259 318.097 558.96 c
318.097 555.661 315.419 552.983 312.12 552.983 c
308.821 552.983 306.143 555.661 306.143 558.96 c
306.143 562.259 308.821 564.937 312.12 564.937 c
f
0.459 0.459 0.459 sc
312.06 564.952 m
315.301 564.952 317.932 562.321 317.932 559.08 c
317.932 555.839 315.301 553.208 312.06 553.208 c
308.819 553.208 306.188 555.839 306.188 559.08 c
306.188 562.321 308.819 564.952 312.06 564.952 c
f
0.482 0.482 0.482 sc
311.94 564.968 m
315.124 564.968 317.708 562.384 317.708 559.2 c
317.708 556.016 315.124 553.432 311.94 553.432 c
308.756 553.432 306.172 556.016 306.172 559.2 c
306.172 562.384 308.756 564.968 311.94 564.968 c
f
0.506 0.506 0.506 sc
311.94 564.983 m
315.066 564.983 317.603 562.446 317.603 559.32 c
317.603 556.194 315.066 553.657 311.94 553.657 c
308.814 553.657 306.277 556.194 306.277 559.32 c
306.277 562.446 308.814 564.983 311.94 564.983 c
f
0.525 0.525 0.525 sc
311.88 564.998 m
314.948 564.998 317.438 562.508 317.438 559.44 c
317.438 556.372 314.948 553.882 311.88 553.882 c
308.812 553.882 306.322 556.372 306.322 559.44 c
306.322 562.508 308.812 564.998 311.88 564.998 c
f
0.549 0.549 0.549 sc
311.76 565.014 m
314.771 565.014 317.214 562.571 317.214 559.56 c
317.214 556.549 314.771 554.106 311.76 554.106 c
308.749 554.106 306.306 556.549 306.306 559.56 c
306.306 562.571 308.749 565.014 311.76 565.014 c
f
0.569 0.569 0.569 sc
311.76 565.029 m
314.713 565.029 317.109 562.633 317.109 559.68 c
317.109 556.727 314.713 554.331 311.76 554.331 c
308.807 554.331 306.411 556.727 306.411 559.68 c
306.411 562.633 308.807 565.029 311.76 565.029 c
f
0.584 0.584 0.584 sc
311.7 565.045 m
314.595 565.045 316.945 562.695 316.945 559.8 c
316.945 556.905 314.595 554.555 311.7 554.555 c
308.805 554.555 306.455 556.905 306.455 559.8 c
306.455 562.695 308.805 565.045 311.7 565.045 c
f
0.604 0.604 0.604 sc
311.64 565.06 m
314.477 565.06 316.78 562.757 316.78 559.92 c
316.78 557.083 314.477 554.78 311.64 554.78 c
308.803 554.78 306.5 557.083 306.5 559.92 c
306.5 562.757 308.803 565.06 311.64 565.06 c
f
0.624 0.624 0.624 sc
311.58 565.075 m
314.36 565.075 316.615 562.82 316.615 560.04 c
316.615 557.26 314.36 555.005 311.58 555.005 c
308.8 555.005 306.545 557.26 306.545 560.04 c
306.545 562.82 308.8 565.075 311.58 565.075 c
f
0.643 0.643 0.643 sc
311.46 565.091 m
314.182 565.091 316.391 562.882 316.391 560.16 c
316.391 557.438 314.182 555.229 311.46 555.229 c
308.738 555.229 306.529 557.438 306.529 560.16 c
306.529 562.882 308.738 565.091 311.46 565.091 c
f
0.663 0.663 0.663 sc
311.46 565.106 m
314.124 565.106 316.286 562.944 316.286 560.28 c
316.286 557.616 314.124 555.454 311.46 555.454 c
308.796 555.454 306.634 557.616 306.634 560.28 c
306.634 562.944 308.796 565.106 311.46 565.106 c
f
0.678 0.678 0.678 sc
311.4 565.122 m
314.006 565.122 316.122 563.006 316.122 560.4 c
316.122 557.794 314.006 555.678 311.4 555.678 c
308.794 555.678 306.678 557.794 306.678 560.4 c
306.678 563.006 308.794 565.122 311.4 565.122 c
f
0.698 0.698 0.698 sc
311.28 565.137 m
313.829 565.137 315.897 563.069 315.897 560.52 c
315.897 557.971 313.829 555.903 311.28 555.903 c
308.731 555.903 306.663 557.971 306.663 560.52 c
306.663 563.069 308.731 565.137 311.28 565.137 c
f
0.714 0.714 0.714 sc
311.28 565.152 m
313.771 565.152 315.793 563.131 315.793 560.64 c
315.793 558.149 313.771 556.128 311.28 556.128 c
308.789 556.128 306.768 558.149 306.768 560.64 c
306.768 563.131 308.789 565.152 311.28 565.152 c
f
0.729 0.729 0.729 sc
311.22 565.168 m
313.653 565.168 315.628 563.193 315.628 560.76 c
315.628 558.327 313.653 556.352 311.22 556.352 c
308.787 556.352 306.812 558.327 306.812 560.76 c
306.812 563.193 308.787 565.168 311.22 565.168 c
f
0.745 0.745 0.745 sc
311.16 565.183 m
313.535 565.183 315.463 563.255 315.463 560.88 c
315.463 558.505 313.535 556.577 311.16 556.577 c
308.785 556.577 306.857 558.505 306.857 560.88 c
306.857 563.255 308.785 565.183 311.16 565.183 c
f
0.761 0.761 0.761 sc
311.1 565.139 m
313.418 565.139 315.299 563.258 315.299 560.94 c
315.299 558.622 313.418 556.741 311.1 556.741 c
308.782 556.741 306.901 558.622 306.901 560.94 c
306.901 563.258 308.782 565.139 311.1 565.139 c
f
0.776 0.776 0.776 sc
311.04 565.214 m
313.3 565.214 315.134 563.38 315.134 561.12 c
315.134 558.86 313.3 557.026 311.04 557.026 c
308.78 557.026 306.946 558.86 306.946 561.12 c
306.946 563.38 308.78 565.214 311.04 565.214 c
f
0.792 0.792 0.792 sc
310.98 565.23 m
313.182 565.23 314.97 563.442 314.97 561.24 c
314.97 559.038 313.182 557.25 310.98 557.25 c
308.778 557.25 306.99 559.038 306.99 561.24 c
306.99 563.442 308.778 565.23 310.98 565.23 c
f
0.804 0.804 0.804 sc
310.92 565.245 m
313.064 565.245 314.805 563.505 314.805 561.36 c
314.805 559.216 313.064 557.475 310.92 557.475 c
308.776 557.475 307.035 559.216 307.035 561.36 c
307.035 563.505 308.776 565.245 310.92 565.245 c
f
0.82 0.82 0.82 sc
310.8 565.26 m
312.887 565.26 314.58 563.567 314.58 561.48 c
314.58 559.393 312.887 557.7 310.8 557.7 c
308.713 557.7 307.02 559.393 307.02 561.48 c
307.02 563.567 308.713 565.26 310.8 565.26 c
f
0.831 0.831 0.831 sc
310.8 565.276 m
312.829 565.276 314.476 563.629 314.476 561.6 c
314.476 559.571 312.829 557.924 310.8 557.924 c
308.771 557.924 307.124 559.571 307.124 561.6 c
307.124 563.629 308.771 565.276 310.8 565.276 c
f
0.843 0.843 0.843 sc
310.74 565.291 m
312.711 565.291 314.311 563.691 314.311 561.72 c
314.311 559.749 312.711 558.149 310.74 558.149 c
308.769 558.149 307.169 559.749 307.169 561.72 c
307.169 563.691 308.769 565.291 310.74 565.291 c
f
0.855 0.855 0.855 sc
310.68 565.307 m
312.594 565.307 314.147 563.754 314.147 561.84 c
314.147 559.927 312.594 558.373 310.68 558.373 c
308.766 558.373 307.213 559.927 307.213 561.84 c
307.213 563.754 308.766 565.307 310.68 565.307 c
f
0.867 0.867 0.867 sc
310.62 565.262 m
312.476 565.262 313.982 563.756 313.982 561.9 c
313.982 560.044 312.476 558.538 310.62 558.538 c
308.764 558.538 307.258 560.044 307.258 561.9 c
307.258 563.756 308.764 565.262 310.62 565.262 c
f
0.878 0.878 0.878 sc
310.56 565.337 m
312.358 565.337 313.817 563.878 313.817 562.08 c
313.817 560.282 312.358 558.823 310.56 558.823 c
308.762 558.823 307.303 560.282 307.303 562.08 c
307.303 563.878 308.762 565.337 310.56 565.337 c
f
0.894 0.89 0.894 sc
310.5 565.353 m
312.24 565.353 313.653 563.94 313.653 562.2 c
313.653 560.46 312.24 559.047 310.5 559.047 c
308.76 559.047 307.347 560.46 307.347 562.2 c
307.347 563.94 308.76 565.353 310.5 565.353 c
f
0.902 0.898 0.902 sc
310.44 565.368 m
312.123 565.368 313.488 564.003 313.488 562.32 c
313.488 560.637 312.123 559.272 310.44 559.272 c
308.757 559.272 307.392 560.637 307.392 562.32 c
307.392 564.003 308.757 565.368 310.44 565.368 c
f
0.914 0.914 0.914 sc
310.32 565.384 m
311.945 565.384 313.264 564.065 313.264 562.44 c
313.264 560.815 311.945 559.496 310.32 559.496 c
308.695 559.496 307.376 560.815 307.376 562.44 c
307.376 564.065 308.695 565.384 310.32 565.384 c
f
0.922 0.922 0.922 sc
310.32 565.399 m
311.887 565.399 313.159 564.127 313.159 562.56 c
313.159 560.993 311.887 559.721 310.32 559.721 c
308.753 559.721 307.481 560.993 307.481 562.56 c
307.481 564.127 308.753 565.399 310.32 565.399 c
f
0.929 0.929 0.929 sc
310.26 565.414 m
311.769 565.414 312.994 564.189 312.994 562.68 c
312.994 561.171 311.769 559.946 310.26 559.946 c
308.751 559.946 307.526 561.171 307.526 562.68 c
307.526 564.189 308.751 565.414 310.26 565.414 c
f
0.937 0.937 0.937 sc
310.2 565.37 m
311.652 565.37 312.83 564.192 312.83 562.74 c
312.83 561.288 311.652 560.11 310.2 560.11 c
308.748 560.11 307.57 561.288 307.57 562.74 c
307.57 564.192 308.748 565.37 310.2 565.37 c
f
0.945 0.945 0.945 sc
310.14 565.385 m
311.534 565.385 312.665 564.254 312.665 562.86 c
312.665 561.466 311.534 560.335 310.14 560.335 c
308.746 560.335 307.615 561.466 307.615 562.86 c
307.615 564.254 308.746 565.385 310.14 565.385 c
f
0.953 0.953 0.953 sc
310.08 565.461 m
311.416 565.461 312.501 564.376 312.501 563.04 c
312.501 561.704 311.416 560.619 310.08 560.619 c
308.744 560.619 307.659 561.704 307.659 563.04 c
307.659 564.376 308.744 565.461 310.08 565.461 c
f
0.957 0.957 0.957 sc
310.02 565.476 m
311.298 565.476 312.336 564.438 312.336 563.16 c
312.336 561.882 311.298 560.844 310.02 560.844 c
308.742 560.844 307.704 561.882 307.704 563.16 c
307.704 564.438 308.742 565.476 310.02 565.476 c
f
0.965 0.965 0.965 sc
309.96 565.491 m
311.181 565.491 312.171 564.501 312.171 563.28 c
312.171 562.059 311.181 561.069 309.96 561.069 c
308.739 561.069 307.749 562.059 307.749 563.28 c
307.749 564.501 308.739 565.491 309.96 565.491 c
f
0.969 0.969 0.969 sc
309.9 565.507 m
311.063 565.507 312.007 564.563 312.007 563.4 c
312.007 562.237 311.063 561.293 309.9 561.293 c
308.737 561.293 307.793 562.237 307.793 563.4 c
307.793 564.563 308.737 565.507 309.9 565.507 c
f
0.976 0.976 0.976 sc
309.84 565.522 m
310.945 565.522 311.842 564.625 311.842 563.52 c
311.842 562.415 310.945 561.518 309.84 561.518 c
308.735 561.518 307.838 562.415 307.838 563.52 c
307.838 564.625 308.735 565.522 309.84 565.522 c
f
0.98 0.98 0.98 sc
309.78 565.538 m
310.828 565.538 311.678 564.688 311.678 563.64 c
311.678 562.593 310.828 561.742 309.78 561.742 c
308.733 561.742 307.882 562.593 307.882 563.64 c
307.882 564.688 308.733 565.538 309.78 565.538 c
f
0.984 0.984 0.984 sc
309.72 565.493 m
310.71 565.493 311.513 564.69 311.513 563.7 c
311.513 562.71 310.71 561.907 309.72 561.907 c
308.73 561.907 307.927 562.71 307.927 563.7 c
307.927 564.69 308.73 565.493 309.72 565.493 c
f
0.988 0.988 0.988 sc
309.66 565.508 m
310.592 565.508 311.348 564.752 311.348 563.82 c
311.348 562.888 310.592 562.132 309.66 562.132 c
308.728 562.132 307.972 562.888 307.972 563.82 c
307.972 564.752 308.728 565.508 309.66 565.508 c
f
0.992 0.992 0.992 sc
309.6 565.584 m
310.474 565.584 311.184 564.874 311.184 564 c
311.184 563.126 310.474 562.416 309.6 562.416 c
308.726 562.416 308.016 563.126 308.016 564 c
308.016 564.874 308.726 565.584 309.6 565.584 c
f
309.54 565.599 m
310.357 565.599 311.019 564.937 311.019 564.12 c
311.019 563.303 310.357 562.641 309.54 562.641 c
308.723 562.641 308.061 563.303 308.061 564.12 c
308.061 564.937 308.723 565.599 309.54 565.599 c
f
0.996 0.996 0.996 sc
309.48 565.615 m
310.239 565.615 310.855 564.999 310.855 564.24 c
310.855 563.481 310.239 562.865 309.48 562.865 c
308.721 562.865 308.105 563.481 308.105 564.24 c
308.105 564.999 308.721 565.615 309.48 565.615 c
f
309.42 565.63 m
310.121 565.63 310.69 565.061 310.69 564.36 c
310.69 563.659 310.121 563.09 309.42 563.09 c
308.719 563.09 308.15 563.659 308.15 564.36 c
308.15 565.061 308.719 565.63 309.42 565.63 c
f
1 1 1 sc
309.36 565.646 m
310.003 565.646 310.525 565.123 310.525 564.48 c
310.525 563.837 310.003 563.315 309.36 563.315 c
308.717 563.315 308.195 563.837 308.195 564.48 c
308.195 565.123 308.717 565.646 309.36 565.646 c
f
309.3 565.601 m
309.886 565.601 310.361 565.126 310.361 564.54 c
310.361 563.954 309.886 563.479 309.3 563.479 c
308.714 563.479 308.239 563.954 308.239 564.54 c
308.239 565.126 308.714 565.601 309.3 565.601 c
f
q
304.28 583.68 233.99 -49.984 re
W n
0.6 w
313.08 564.69 m
317.303 564.69 320.73 561.263 320.73 557.04 c
320.73 552.817 317.303 549.39 313.08 549.39 c
308.857 549.39 305.43 552.817 305.43 557.04 c
305.43 561.263 308.857 564.69 313.08 564.69 c
S
Q
0 0 0 sc
449.58 563.19 m
453.803 563.19 457.23 559.763 457.23 555.54 c
457.23 551.317 453.803 547.89 449.58 547.89 c
445.357 547.89 441.93 551.317 441.93 555.54 c
441.93 559.763 445.357 563.19 449.58 563.19 c
f
0.039 0.039 0.039 sc
449.52 563.206 m
453.685 563.206 457.066 559.825 457.066 555.66 c
457.066 551.495 453.685 548.114 449.52 548.114 c
445.355 548.114 441.974 551.495 441.974 555.66 c
441.974 559.825 445.355 563.206 449.52 563.206 c
f
0.082 0.082 0.082 sc
449.46 563.221 m
453.568 563.221 456.901 559.888 456.901 555.78 c
456.901 551.673 453.568 548.339 449.46 548.339 c
445.353 548.339 442.019 551.673 442.019 555.78 c
442.019 559.888 445.353 563.221 449.46 563.221 c
f
0.118 0.118 0.118 sc
449.4 563.237 m
453.45 563.237 456.737 559.95 456.737 555.9 c
456.737 551.85 453.45 548.563 449.4 548.563 c
445.35 548.563 442.063 551.85 442.063 555.9 c
442.063 559.95 445.35 563.237 449.4 563.237 c
f
0.145 0.145 0.145 sc
449.34 563.252 m
453.332 563.252 456.572 560.012 456.572 556.02 c
456.572 552.028 453.332 548.788 449.34 548.788 c
445.348 548.788 442.108 552.028 442.108 556.02 c
442.108 560.012 445.348 563.252 449.34 563.252 c
f
0.169 0.169 0.169 sc
449.28 563.267 m
453.214 563.267 456.407 560.074 456.407 556.14 c
456.407 552.206 453.214 549.013 449.28 549.013 c
445.346 549.013 442.153 552.206 442.153 556.14 c
442.153 560.074 445.346 563.267 449.28 563.267 c
f
0.196 0.196 0.196 sc
449.16 563.343 m
453.037 563.343 456.183 560.197 456.183 556.32 c
456.183 552.443 453.037 549.297 449.16 549.297 c
445.283 549.297 442.137 552.443 442.137 556.32 c
442.137 560.197 445.283 563.343 449.16 563.343 c
f
0.224 0.224 0.224 sc
449.16 563.298 m
452.979 563.298 456.078 560.199 456.078 556.38 c
456.078 552.561 452.979 549.462 449.16 549.462 c
445.341 549.462 442.242 552.561 442.242 556.38 c
442.242 560.199 445.341 563.298 449.16 563.298 c
f
0.247 0.247 0.247 sc
449.1 563.314 m
452.861 563.314 455.914 560.261 455.914 556.5 c
455.914 552.739 452.861 549.686 449.1 549.686 c
445.339 549.686 442.286 552.739 442.286 556.5 c
442.286 560.261 445.339 563.314 449.1 563.314 c
f
0.275 0.275 0.275 sc
449.04 563.329 m
452.743 563.329 455.749 560.323 455.749 556.62 c
455.749 552.917 452.743 549.911 449.04 549.911 c
445.337 549.911 442.331 552.917 442.331 556.62 c
442.331 560.323 445.337 563.329 449.04 563.329 c
f
0.294 0.294 0.294 sc
448.98 563.344 m
452.626 563.344 455.584 560.386 455.584 556.74 c
455.584 553.094 452.626 550.136 448.98 550.136 c
445.334 550.136 442.376 553.094 442.376 556.74 c
442.376 560.386 445.334 563.344 448.98 563.344 c
f
0.322 0.322 0.322 sc
448.92 563.36 m
452.508 563.36 455.42 560.448 455.42 556.86 c
455.42 553.272 452.508 550.36 448.92 550.36 c
445.332 550.36 442.42 553.272 442.42 556.86 c
442.42 560.448 445.332 563.36 448.92 563.36 c
f
0.349 0.349 0.349 sc
448.86 563.375 m
452.39 563.375 455.255 560.51 455.255 556.98 c
455.255 553.45 452.39 550.585 448.86 550.585 c
445.33 550.585 442.465 553.45 442.465 556.98 c
442.465 560.51 445.33 563.375 448.86 563.375 c
f
0.369 0.369 0.369 sc
448.8 563.391 m
452.272 563.391 455.091 560.572 455.091 557.1 c
455.091 553.628 452.272 550.809 448.8 550.809 c
445.328 550.809 442.509 553.628 442.509 557.1 c
442.509 560.572 445.328 563.391 448.8 563.391 c
f
0.392 0.392 0.392 sc
448.68 563.406 m
452.095 563.406 454.866 560.635 454.866 557.22 c
454.866 553.805 452.095 551.034 448.68 551.034 c
445.265 551.034 442.494 553.805 442.494 557.22 c
442.494 560.635 445.265 563.406 448.68 563.406 c
f
0.42 0.42 0.42 sc
448.68 563.421 m
452.037 563.421 454.761 560.697 454.761 557.34 c
454.761 553.983 452.037 551.259 448.68 551.259 c
445.323 551.259 442.599 553.983 442.599 557.34 c
442.599 560.697 445.323 563.421 448.68 563.421 c
f
0.439 0.439 0.439 sc
448.62 563.437 m
451.919 563.437 454.597 560.759 454.597 557.46 c
454.597 554.161 451.919 551.483 448.62 551.483 c
445.321 551.483 442.643 554.161 442.643 557.46 c
442.643 560.759 445.321 563.437 448.62 563.437 c
f
0.459 0.459 0.459 sc
448.5 563.452 m
451.741 563.452 454.372 560.821 454.372 557.58 c
454.372 554.339 451.741 551.708 448.5 551.708 c
445.259 551.708 442.628 554.339 442.628 557.58 c
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0.663 0.663 0.663 sc
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0.678 0.678 0.678 sc
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0.745 0.745 0.745 sc
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f
0.761 0.761 0.761 sc
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f
0.776 0.776 0.776 sc
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f
0.792 0.792 0.792 sc
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0.82 0.82 0.82 sc
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0.831 0.831 0.831 sc
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0.855 0.855 0.855 sc
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0.867 0.867 0.867 sc
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f
0.878 0.878 0.878 sc
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f
0.902 0.898 0.902 sc
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0.914 0.914 0.914 sc
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f
0.922 0.922 0.922 sc
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f
0.929 0.929 0.929 sc
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f
0.937 0.937 0.937 sc
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f
0.945 0.945 0.945 sc
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f
0.953 0.953 0.953 sc
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f
0.957 0.957 0.957 sc
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f
0.965 0.965 0.965 sc
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f
0.969 0.969 0.969 sc
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f
0.976 0.976 0.976 sc
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f
0.98 0.98 0.98 sc
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f
0.984 0.984 0.984 sc
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f
0.988 0.988 0.988 sc
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f
0.992 0.992 0.992 sc
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f
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f
0.996 0.996 0.996 sc
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f
445.92 564.07 m
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f
1 1 1 sc
445.86 564.146 m
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f
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f
0.6 w
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445.357 547.89 441.93 551.317 441.93 555.54 c
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S
0.48 w
430.315 555.947 m
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S
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f
1 1 1 sc
304.28 517.08 162 -133.08 re
f
0.6 w
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S
BT
7.0003 0 0 7.0003 336.9129 510.4117 Tm
0.161 0.145 0.149 sc
(N)Tj
ET
329.063 494.811 m
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f
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f
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f
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f
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f
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f
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f
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f
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f
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f
318.312 488.311 m
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f
BT
7.0003 0 0 7.0003 315.2121 473.3102 Tm
(OH)Tj
ET
318.312 479.51 m
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317.762 488.611 l
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318.312 488.311 l
f
BT
7.0003 0 0 7.0003 368.8141 491.861 Tm
(O)Tj
ET
367.814 494.061 m
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f
368.914 492.111 m
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f
BT
7.0003 0 0 7.0003 358.1137 473.3102 Tm
(OH)Tj
ET
361.214 479.51 m
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361.214 488.611 l
f
BT
7.0003 0 0 7.0003 390.2649 492.561 Tm
(Br)Tj
ET
398.715 496.211 m
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f
407.366 501.211 m
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f
BT
7.0003 0 0 7.0003 425.9662 498.7612 Tm
(O)Tj
ET
418.066 495.011 m
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f
431.766 499.511 m
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f
439.517 495.011 m
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f
BT
7.0003 0 0 7.0003 458.4174 492.561 Tm
(Br)Tj
ET
450.217 501.211 m
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457.817 497.511 l
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f
444.57 492.061 m
445.317 492.061 l
445.317 504.011 l
444.57 504.011 l
S
BT
6.0002 0 0 6.0003 446.967 490.0109 Tm
(3)Tj
/TT4 1 Tf
5.0002 0 0 5.0002 383.4146 493.711 Tm
(+)Tj
/TT8 1 Tf
7.0003 0 0 7.0003 381.6646 446.009 Tm
(N)Tj
ET
373.814 430.408 m
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f
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f
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f
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f
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f
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f
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f
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f
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f
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f
363.114 423.858 m
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f
BT
7.0003 0 0 7.0003 349.3134 427.4582 Tm
(O)Tj
ET
354.514 427.208 m
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362.964 423.008 l
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f
355.614 429.158 m
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f
BT
7.0003 0 0 7.0003 360.0138 408.8575 Tm
(O)Tj
ET
363.114 415.108 m
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362.514 424.208 l
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363.114 423.858 l
f
BT
7.0003 0 0 7.0003 413.6158 427.4582 Tm
(O)Tj
ET
412.616 429.658 m
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404.765 424.458 l
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f
413.716 427.708 m
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f
BT
7.0003 0 0 7.0003 402.9153 408.8575 Tm
(O)Tj
ET
406.015 415.108 m
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406.015 424.208 l
f
363.114 399.457 m
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f
406.015 399.107 m
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406.015 407.857 l
f
394.965 392.757 m
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406.015 399.107 l
f
373.564 393.407 m
373.564 392.757 l
362.514 399.107 l
362.814 399.307 l
363.114 399.457 l
f
BT
7.0003 0 0 7.0003 381.4646 396.5069 Tm
(O)Tj
ET
380.965 397.707 m
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