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Cent Eur Neurosurg 2004; 65(4): 180-184
DOI: 10.1055/s-2004-832349
Original Article

© Georg Thieme Verlag Stuttgart · New York

Spontaneous, Multiple Meningiomas

Spontane multiple MeningeomeM. Salvati1 , E. Caroli2 , L. Ferrante2 , G. Rocchi2 , G. D' Andrea2 , M. Piccirilli2 , R. Delfini2
  • 1Department of Neurosurgery, INM Neuromed IRCCS, Pozzilli (Is), Italy
  • 2Department of Neurological Sciences, Neurosurgery, Policlinico Umberto I, University of Rome “La Sapienza”, Rome, Italy
Further Information

Publication History

Publication Date:
18 November 2004 (online)

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Abstract

Object: The aim of this study is to discuss the management strategy of patients with multiple meningiomas.
Methods: We describe 35 patients with multiple meningiomas. No patients carried stigmata of neurofibromatosis. All patients were studied using MR or CT after surgical treatment.
Results: All 35 patients received surgical treatment. A total of 40 operations was performed. The resection of 4 meningiomas was subtotal and all other tumors were radically resected. We had excellent results with reversible operative complications in only three patients. There were no recurrences.
Conclusions: We suggest that surgery is suitable for the treatment of multiple meningiomas with the following characteristics: symptomatic meningioma, asymptomatic meningioma greater than 3 cm in size and surgically accessible, and asymptomatic expanding tumor.
In patients with multiple tumors, each tumor must be treated as an individual entity. The mere presence of multiple tumors does not justify their removal.

Zusammenfassung

Ziel: Ziel der Studie ist es, die Behandlungsstrategie bei Patienten mit multiplen Meningeomen zu diskutieren.
Methoden: Es werden 35 Patienten mit multiplen Meningeomen beschrieben. Keiner der Patienten wies die Zeichen einer Neurofibromatose auf. Alle Patienten wurden nach der Operation mit MR oder CT untersucht.
Ergebnisse: Alle 35 Patienten wurden operiert. Insgesamt wurden 40 Operationen durchgeführt. In 4 Fällen war die Entfernung der Meningeome subtotal, alle anderen Tumoren wurden radikal entfernt. Wir stufen die Ergebnisse als exzellent ein mit nur je einer reversiblen operativen Komplikation bei 3 Patienten. Bisher wurden keine Rezidive beobachtet.
Schlussfolgerungen: Wir votieren für operatives Vorgehen bei multiplen Meningeomen mit den folgenden Charakteristika: Symptomatische Meningeome, asymptomatische Meningeome größer als 3 cm und chirurgisch erreichbar sowie asymptomatisch wachsende Tumoren. Bei Patienten mit multiplen Tumoren sollte jeder Tumor als eine separate Entität behandelt werden. Die bloße Präsenz von multiplen Tumoren rechtfertigt noch nicht ihre Entfernung.

Key words

Multiple meningiomas - management

Schlüsselwörter

Multiple Meningeome - Meningeom

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Dr. Emanuela Caroli

Via Meropia, 85

00147 Rome

Italy

Fax: +39/206-47 88 80 54

Email: manucarol2000@yahoo.it

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