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Radiologie up2date 2004; 4(1): 37-56
DOI: 10.1055/s-2004-820585
Interventionelle Radiologie
© Georg Thieme Verlag Stuttgart · New York

Stellenwert der strukturellen und funktionellen Bildgebung bei Demenzen

The Value of Structural and Functional Imaging in DementiaFrank  Hentschel1
  • 1Abteilung Neuroradiologie ZI, Fakultät für klinische Medizin Mannheim der Universität Heidelberg
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Publication History

Publication Date:
04 March 2004 (online)

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Zusammenfassung

Die bildgebende strukturelle und funktionelle Diagnostik liefert einen eigenen Beitrag zur klinischen Diagnostik und Differenzialdiagnostik der Demenzen. Die Analyse der strukturellen Veränderungen, Hirnatrophie bzw. Läsionen des Hirnparenchyms ist mit sensitiven (Magnetresonanz-)Untersuchungstechniken vergleichsweise einfach, die Ergebnisse besitzen bei isolierter Betrachtung aber nur eine geringe Spezifität. Zunehmend bekommen neben der Magnetresonanzspektroskopie funktionelle, aus der strukturellen Bildgebung abgeleitete Untersuchungsmethoden wie Magnetization Transfer Ratio (MTR) oder Diffusion Tensor Imaging (DTI) bzw. die funktionelle MRT eine Bedeutung. Gesicherte Ergebnisse der strukturellen und funktionellen Bildgebung werden für diagnostisch und differenzialtherapeutisch bedeutsame Demenzerkrankungen dargestellt und orientierend mit den Ergebnissen der Nuklearmedizin verglichen.

Abstract

Structural and functional diagnostic imaging provides a distinctive contribution to the clinical and differential diagnosis in dementia. Sensitive magnetic resonance techniques make the analysis of structural changes, brain atrophy and lesions of the cerebral parenchyma relatively simple, but a particular finding only has a low specificity. Magnetic resonance spectroscopy and innovative structural techniques, such as magnetization transfer ratio (MTR), diffusion tensor imaging (DTI) and functional magnetic resonance tomography, become increasingly important. Results of structural and functional diagnostic imaging are documented in reference to their diagnostic and differential therapeutic contribution to relevant dementias and are cautiously compared with the results of nuclear medicine.

Key words

Dementias, - Diagnostics, - Imaging, - Radiology, - Nuclear Medicine

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Korrespondenzadresse

Prof. Dr. Frank Hentschel

Abteilung Neuroradiologie ZI Fakultät für klinische Medizin Mannheim der Universität Heidelberg

68159 Mannheim J5

Phone: +49 621 1703-864

Fax: +49 621 1703-137

Email: hentsche@zi-mannheim.de

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