Synthesis 2022(6): 901-904  
DOI: 10.1055/s-2004-816013
PAPER
© Georg Thieme Verlag Stuttgart · New York

Ag3PW12O40: A Novel and Recyclable Heteropoly Acid for the Synthesis of 1,5-Benzodiazepines under Solvent-Free Conditions

J. S. Yadav*, B. V. S. Reddy, S. Praveenkumar, K. Nagaiah, N. Lingaiah, P. S. Saiprasad
Indian Institute of Chemical Technology, Hyderabad-500 007, India
Fax: +91(40)27160512; e-Mail: yadav@iict.ap.nic.in;
Further Information

Publication History

Received 16 December 2003
Publication Date:
15 March 2004 (online)

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Abstract

o-Phenylenediamines undergo smooth condensation with ketones having hydrogens at α-position on the surface of heteropoly acid (Ag3PW12O40) under extremely mild conditions to afford the corresponding 1,5-benzodiazepines in excellent yields with high selectivity. The catalyst can be recovered by simple filteration and can be reused in subsequent reactions.

Keywords

heteropoly acids - o-phenylenediamines - ketones - benzodiazepines

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