DDW Reports 2003 Orlando: Reflux Disease and Barrett’s Esophagus

Gastroesophageal reflux disease (GERD) and Barrett’s esophagus (BE) continue to be major topics in the field of clinical research. More data are accumulating on the endoscopic diagnosis of subtle abnormalities, to allow better classification of patients into endoscopy-positive and endoscopy-negative (NERD, non-erosive reflux disease) groups. The situation regarding endoscopic antireflux techniques has not become much clearer. Some abstracts were presented to both societies.

References

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• 3 Lin E, Waring J P, Ramaswamy A. et al . Analysis of 245 consecutive studies using 48-hour wireless pH (Bravo) probes for GERD evaluation [abstract].  Gastrointest Endosc. 2003;  57 AB 100
• 4 Novak D J, Williams D C, Mayer K A. et al . Day-to-day variability in reflux events using the Bravo pH monitoring system [abstract].  Gastrointest Endosc. 2003;  57 AB 133
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• 6 Rhoads S, Goel S, Fogel R. et al . A large proportion of patients with symptomatic reflux disease are ineligible for endoscopic therapy [abstract].  Gastrointest Endosc. 2003;  57 AB 119
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• 19 De Angelis C, Repici A, Dughera L. et al . EUS-assisted Stretta procedure for GERD treatment and EUS assessment of immediate and delayed radiofrequency (RF)-related gastroesophageal (GE) wall changes [abstract].  Gastrointest Endosc. 2003;  57 AB 131
• 20 Noar M, Xu L, Koch K L. Effect of radiofrequency ablation on gastric dysrhythmias and gastric emptying in patients with gastroesophageal reflux disease (GERD) and functional dyspepsia [abstract].  Gastroenterology. 2003;  124 A 98
• 21 Noar M D, Lotfi S. Radiofrequency (RF) energy ablation of the cardia and esophagogastric junction corrects GERD-associated gastroparesis [abstract].  Gastrointest Endosc. 2003;  57 AB 97
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• 29 Louis H, Van Gansbeke D, Silverman D. et al . Three years follow-up for initial GERD patients injected with EVOH polymer [abstract].  Gastroenterology. 2003;  124 A 419
• 30 Fockens P, Bruno M J, Costamagna G. et al . Endoscopic augmentation of the lower esophageal sphincter for the treatment of GERD: multicenter study of the Gatekeeper reflux repair system [abstract].  Gastrointest Endosc. 2003;  57 AB 97
• 31 Emerenziani S, Gabbrielli A, Cicala M. et al . Effect of Gatekeeper reflux repair system on intra-esophageal distribution of acid reflux in gastroesophageal reflux disease patients: relation with typical symptoms [abstract].  Gastroenterology. 2003;  124 A 418
• 32 Voderholzer W, Fielder T, Johannsen S. et al . Interventional endoscopic therapy of gastroesophageal reflux disease: Enteryx vs. Endocinch [abstract].  Gastroenterology. 2003;  124 A 38
• 33 Harewood G C, Gostout C J. Cost analysis of endoscopic anti-reflux procedures: endoluminal plication versus radiofrequency versus proton pump inhibitor [abstract].  Gastrointest Endosc. 2003;  57 AB 98
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• 38 Harewood G C. Variation in detection of Barrett’s esophagus: results from a national endoscopic database [abstract].  Gastrointest Endosc. 2003;  57 AB 134
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• 40 van Zanten S V, Thomson A, Barkun A. et al . The prevalence of Barrett’s esophagus in primary care patients with uninvestigated dyspepsia [abstract].  Gastroenterology. 2003;  124 A 644
• 41 Vieth M, Leodolter A, Kulig M. et al . What causes discrepancies between the endoscopic and histological diagnosis of Barrett’s epithelium? A report from the ProGerd study initiative [abstract].  Gastroenterology. 2003;  124 A 639
• 42 Banwait K S, Banwait P S, DiMarino A. et al . Endoscopic impression of Barrett esophagus: declining positive predictive value [abstract].  Gastroenterology. 2003;  124 A 642
• 43 Falk G W, Trolli P A, Gramlich T L. Surveillance of Barrett’s esophagus by a modified nonendoscopic cytology device: final results [abstract].  Gastrointest Endosc. 2003;  57 AB 135
• 44 Dekel R, Wakelin D E, Wendel C. et al . Progression or regression of Barrett’s esophagus: is it all in the eye of the beholder? [abstract].  Gastrointest Endosc. 2003;  57 AB 138
• 45 Tewari V, Tewari D, Solanki K. et al . Assessment of squamocolumnar junction in distal esophagus using ZAP classification [abstract].  Gastrointest Endosc. 2003;  57 AB 136
• 46 Rey J F, Kuznetsov K. Usefulness of chromoscopy with acetic acid and magnification for Barrett esophagus [abstract].  Gastrointest Endosc. 2003;  57 AB 91
• 47 Meining A, Heldwein W. Magnification endoscopy for detection of specialized intestinal metaplasia at the esophagogastric junction [abstract].  Gastrointest Endosc. 2003;  57 AB 92
• 48 Sorbi D, Burgart L J, Zinsmeister A R. et al . Intestinal metaplasia of the cardia: the controversy continues [abstract].  Gastrointest Endosc. 2003;  57 AB 157
• 49 Gerson L B, Green C, Fass R. et al . The impact of body mass index, GERD symptom duration, tobacco and alcohol consumption, and family history on a Barrett’s esophagus prediction model [abstract].  Gastrointest Endosc. 2003;  57 AB 137
• 50 Eisen G M, Heubner E S, de Garmo P. et al . Risk factors for Barrett’s esophagus: the clinical outcomes research initiative (CORI) experience [abstract].  Gastrointest Endosc. 2003;  57 AB 137
• 51 Faulx A L, Hansen G T, Cooper G S. et al . Unsedated screening esophagoscopy (USE) does not impact on primary care physician (PCP) screening practices [abstract].  Gastrointest Endosc. 2003;  57 AB 137
• 52 Chak A, Kinnard M, Brock W. et al . Familial Barrett’s esophagus versus sporadic disease: endoscopic screening of relatives [abstract].  Gastrointest Endosc. 2003;  57 AB 135
• 53 Glenn T, Wildi S M, Wallace M B. et al . Prevalence of Barrett’s esophagus and dysplasia in an unselected GERD population using an battery-powered endoscope (BPE) operated by a nurse practitioner (NP) [abstract].  Gastrointest Endosc. 2003;  57 AB 135
• 54 Solaymani-Dodaran M, Coupland C, Logan R FA. Risk of oesophageal cancer in Barrett’s oesophagus and in gastro-oesophageal reflux [abstract].  Gastroenterology. 2003;  124 A 33
• 55 Sontag S J, Schnell T G, Leya J. et al . The optimal Barrett’s esophagus (BE) cancer surveillance strategy: detecting all while missing none - 23 years of closely followed outcomes [abstract].  Gastrointest Endosc. 2003;  57 AB 134
• 56 Owens M, Blount P, Longton G. et al . Predictors of progression to cancer in Barrett’s esophagus (BE): endoscopic lesions arising from Barrett’s epithelium are not independently associated with increased risk [abstract].  Gastroenterology. 2003;  124 A 643 - -A 644
• 57 Bergman J J, Kara M A, Smits M E. et al . A randomized cross-over study comparing light-induced fluorescence endoscopy (LIFE) with standard endoscopy for detection of early neoplasia in Barrett’s esophagus (BE) [abstract].  Gastroenterology. 2003;  124 A 49
• 58 Borovicka J, Fischer J, Neuweiler J. et al . Surveillance by autofluorescence versus white light endoscopy in Barrett’s esophagus: a prospective multicenter trial [abstract].  Gastrointest Endosc. 2003;  57 AB 136
• 59 Sharma P, McGregor D, Cherian R. et al . Use of narrow band imaging, a novel imaging technique, to detect intestinal metaplasia and high-grade dysplasia in patients with Barrett’s esophagus [abstract].  Gastrointest Endosc. 2003;  57 AB 77
• 60 Wong Kee Song L M, Gao T, Molckovsky A. et al . Accuracy of near-infrared Raman spectroscopy for differentiating adenocarcinoma from high-grade dysplasia in Barrett’s esophagus [abstract].  Gastroenterology. 2003;  124 A 71
• 61 Wong Kee Song L M, Gao T, Molckovsky A. et al . Accuracy of near-infrared Raman spectroscopy for differentiating adenocarcinoma from high-grade dysplasia in Barrett’s esophagus [abstract].  Gastrointest Endosc. 2003;  57 AB 901
• 62 Wong Kee Song L M, Molckovsky A, Buttar N. et al . Characterization of intestinal metaplasia by near-infrared Raman spectroscopy in patients with dysplastic and non-dysplastic Barrett’s esophagus [abstract].  Gastroenterology. 2003;  124 A 644
• 63 Isenberg G, Sivak M V, Chak A. et al . Accuracy of endoscopic optical coherence tomography (EOCT) in the detection of dysplasia (D) in Barrett’s esophagus (BE) [abstract].  Gastrointest Endosc. 2003;  57 AB 77
• 64 Pacifico R, Wang K, Buttar N. et al . Surveillance of Barrett’s esophagus using brush cytology and digital image analysis: a randomized prospective trial [abstract].  Gastrointest Endosc. 2003;  57 AB 91
• 65 Borovicka J, Binek J, Fischer J. et al . Image cytometry identifies high-risk patients with Barrett’s esophagus: a prospective multicenter trial [abstract].  Gastrointest Endosc. 2003;  57 AB 91
• 66 Skacel M, Fahmy M, Gramlich T L. et al . Fluorescence in situ hybridization (FISH) of endoscopic brush cytology from Barrett’s esophagus detects genetic changes in high-grade dysplasia and adenocarcinoma not seen in patients without dysplasia [abstract].  Gastrointest Endosc. 2003;  57 AB 92
• 67 Sayuk G S, Wang H L, Prakash C. Comparison of endoscopic findings to histopathologic examination in the diagnosis of Barrett’s esophagus [abstract].  Gastrointest Endosc. 2003;  57 AB 138
• 68 Ramji A, Chaun H, Halparin L. et al . Trends in the diagnosis and monitoring of Barrett’s esophagus [abstract].  Gastrointest Endosc. 2003;  57 AB 136
• 69 Shaheen N, Inadomi J M, Sharma P. et al . What is the best management strategy for high grade dysplasia (HGD) in Barrett’s esophagus? A cost-effectiveness analysis [abstract].  Gastroenterology. 2003;  124 A 33
• 70 Vij R, Triadafilopoulos G, Owens D K. et al . Cost-effectiveness analysis of photodynamic therapy for treatment of high-grade dysplasia in Barrett’s esophagus [abstract].  Gastrointest Endosc. 2003;  57 AB 79
• 71 Provenzale D. Immediate esophagectomy or surveillance for Barrett’s patients with high grade dysplasia [abstract].  Gastroenterology. 2003;  124 A 506
• 72 Said A, Rice J C, Remington P. et al . Surveillance endoscopy does not impact survival of patients with Barrett’s esophagus [abstract].  Gastroenterology. 2003;  124 A 638 - -A 639
• 73 Behrens A, Pech O, May A. et al . Curative endoscopic therapy of early cancer and high-grade neoplasia in Barrett’s esophagus: additional endoscopic ablation of Barrett’s esophagus can reduce the risk of recurrent carcinomas [abstract].  Gastroenterology. 2003;  124 A 637
• 74 Pech O, May A, Gossner L. et al . Long-term results of local endoscopic therapy for intraepithelial high-grade neoplasia and early adenocarcinoma in Barrett’s esophagus [abstract].  Gastrointest Endosc. 2003;  57 AB 100
• 75 Grimm H, Sherif Y E, Schniewind B. et al . Removal of the complete Barrett’s mucosa (BM) in patients with high-grade dysplasia (HGD) or superficial cancer (SC) by stepwise endoscopic mucosal resection (EMR) [abstract].  Gastrointest Endosc. 2003;  57 AB 139
• 76 Overholt B F, Lightdale C J, Wang K. et al . International multicenter, partially blinded, randomized study of the efficacy of photodynamic therapy (PDT) using porfimer sodium (POR) for ablation of high-grade dysplasia (HGD) in Barrett’s esophagus (BE): results of 24-month follow-up [abstract].  Gastroenterology. 2003;  124 A 20
• 77 Tam W, Ackroyd R, Watson D. et al . Ablation of Barrett’s esophagus with argon plasma coagulation in reflux patients treated with surgical and medical therapy: a randomized controlled trial [abstract].  Gastroenterology. 2003;  124 A 33
• 78 Hage M, VanDekken H, Haringsma J. et al . 5-Aminolevulinic acid-based photodynamic therapy versus argon plasma coagulation for ablation of Barrett’s esophagus: a randomized trial [abstract].  Gastrointest Endosc. 2003;  57 AB 138
• 79 Zoepf T, Alsenbesy M, Jakobs R. et al . Photodynamic therapy (PDT) versus argon plasma coagulation (APC) for ablative therapy of Barrett’s esophagus [abstract].  Gastrointest Endosc. 2003;  57 AB 139
• 80 Ganz R, Zelickson B, Stern R. et al . A method of endoscopic esophageal mucosal ablation using a novel RF energy balloon catheter (BARRX): response characteristics [abstract].  Gastrointest Endosc. 2003;  57 AB 139
• 81 Reeves J, Meeson S, Birch M. et al . Preliminary results from in vivo tests of a microwave application designed to treat Barrett’s esophagus [abstract].  Gastrointest Endosc. 2003;  57 AB 139
• 82 Rajan E, Gostout C J, Feitoza A. et al . Widespread endoscopic mucosal resection (WEMR) of the esophagus in a porcine model using a prototype endoscopic cap device [abstract].  Gastrointest Endosc. 2003;  57 AB 86
• 83 Hino S, Laurence B, Matsuda K. et al . A new material to aid endoscopic mucosal resection (EMR) [abstract].  Gastrointest Endosc. 2003;  57 AB 86