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Int J Sports Med 2003; 24(4): 258-263
DOI: 10.1055/s-2003-39507
Physiology & Biochemistry
© Georg Thieme Verlag Stuttgart · New York

Aerobic Capacity and Peripheral Skeletal Muscle Function in Coronary Artery Disease Male Patients

M.  Gayda1 , A.  Merzouk1 , D.  Choquet1, 2 , P. L.  Doutrellot1, 2, 3 , S.  Ahmaidi1
  • 1Laboratoire de recherche EA 3300 ”APS et Conduites Motrices: Adaptations et Réadaptations“, Faculté des Sciences du Sport, Université de Picardie Jules Verne, 80025 Amiens Cedex 1, France
  • 2Centre de Réadaptation Cardiaque, Hôpital de Corbie, 80800 Corbie, France
  • 3Service d’Explorations Fonctionnelles de l’Appareil Locomoteur, CHU-Nord, 80054 Amiens Cedex, France
Further Information

Publication History

Accepted after revision: December 3, 2002

Publication Date:
04 June 2003 (online)

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Abstract

The aim of this study was to determine if the diminished aerobic capacity of coronary artery disease male (CAD) patients is accompanied by an impaired skeletal muscle function compared to healthy control subjects. Thirteen CAD patients and 9 healthy subjects performed both a maximal laboratory exercise testing and an assessment of the peripheral skeletal muscle function on an isokinetic apparatus. The cardiorespiratory and mechanical parameters were measured at ventilatory threshold and at maximal effort during a maximal exercise testing. The peripheral skeletal muscle function of the quadriceps was assessed from the maximal voluntary isometric force (MVIF) and from the static endurance time (SET) at an intensity of 50 % of the MVIF. The CAD patients showed a diminished aerobic capacity compared to healthy control subjects at maximal effort (maximal V˙O2uptake: p < 0.0001, maximal ventilation: p < 0.01; maximal heart rate: p < 0.0001, maximal power: p < 0.001) but also at VT (V˙O2uptake VT: p < 0.0001, Power VT: p < 0.001). No difference was found on the MVIF (p < 0.90) between the CAD patients and the control subjects whereas the SET was lower in the CAD patients (p < 0.01). The CAD patients had a lower aerobic capacity and an impaired skeletal muscle endurance compared to healthy subjects.

Key words

Coronary artery disease patients - cardiorespiratory capacity - skeletal muscle fatigue

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S. Ahmaidi

Laboratoire de Recherches “EA 3300 · APS et Conduites Motrices: Adaptations et Réadaptations”

Faculté des Sciences du Sport · Allée P. Grousset · 80025, Amiens 6 · France ·

Phone: (33) 3 22 82 79 03

Fax: (33) 3 22 82 79 10

Email: said.ahmaidi@u-picardie.fr

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