Metallo-Enzyme Model in Pure Water: Cyclodextrin-Lanthanide Tris(perfluoroalkanesulfonyl)methide and Bis(perfluoroalkanesulfonyl)amide Complexes

Abstract

Inclusion complexes of cyclodextrin/cyclodextrin co­polymer and lanthanide tris(perfluorobutanesulfonyl)methide/bis(perfluorobutanesulfonyl)amide, namely metallo-enzyme mo­del, are efficient and recyclable super Lewis acid catalysts, which can promote Diels-Alder and Mukaiyama-aldol reactions in pure water.

Key words

cyclodextrin - Lewis acids - catalysis - lanthanides - aqueous reactions

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16

Comm. available from Aldrich Chemical Company, Inc.: Cat. No. 33, 256-9.

18

The full percentage of Ln complex/γ-CDP-Ln complex was found to reach only 60% because of the steric repulsion. Indeed, elemental analysis showed that CDP formed a 59% inclusion complex of Ln(C₄-methide)₃: Calcd Yb, 3.64%. Found: Yb, 3.61%.