Download PDF
Synlett 2001; 2001(9): 1391-1394
DOI: 10.1055/s-2001-16787
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

An Efficient Synthesis of Alkyl Substituted Cyclic 1,3-Diones

Felix S. Pashkovsky* , Igor P. Lokot, Fedor A. Lakhvich
  • *Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus, Kuprevicha str. 5/2, 220141 Minsk, Republic of Belarus; Fax 00375 (17) 2 63 71 32; E-mail: evk@ns.iboch.ac.by
Further Information

Publication History

Publication Date:
28 August 2001 (online)

  PDF Download  Permissions and Reprints All articles of this category

An efficient method for the synthesis of cyclic α-alkyl β-dicarbonyl compounds of cyclopentane, cyclohexane, tetronic acid and α-pyrone series is described. The method consists of the selective transformation of the corresponding cyclic β,β′-tricarbonyl compounds by NaBH3CN in a mixture of THF and 2N aqueous HCl.

cyclic β,β′-triones - sodium cyanoborohydride - selective reduction - cyclic α-alkyl β-diones

      >