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Synlett 2001; 2001(7): 1092-1096
DOI: 10.1055/s-2001-15141
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One Pot Synthesis of New β-Lactams Containing the Ferrocene Moiety

Bianca F. Bonini* , Cristina Femoni, Mauro Comes-Franchini, Mariafrancesca Fochi, Germana Mazzanti, Alfredo Ricci, Greta Varchi
  • *Dipartimento di Chimica Organica "A.Mangini", Università di Bologna, Viale Risorgimento 4, 40136 Bologna, Italy; Fax + 39-051-2 09 36 54; E-mail: bonini@ms.fci.unibo.it
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Publication History

Publication Date:
31 December 2001 (online)

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A new family of β-lactams containing the ferrocene moiety has been synthesized in moderate to excellent yields by a one-pot reaction of ferrocenyl acetic acid and achiral or chiral imines with both the conventional thermal methods and the more rapid microwave irradiation technique. The stereochemical outcome of the reaction is also discussed.

ferrocene - β-lactam - Staudinger reaction - microwave technique - stereochemistry

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