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Synlett 2001; 2001(4): 0519-0520
DOI: 10.1055/s-2001-12321
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N-Bromosuccinimide (NBS), a Novel and Highly Effective Catalyst for Acetylation of Alcohols under Mild Reaction Conditions

Babak Karimi* , Hassan Seradj
  • *Department of Chemistry, Institute for Advanced Studies in Basic Sciences (IASBS), P. O. Box 45195-159, Gava Zang, Zanjan, Iran; Fax + 98(02 41)44 90 23; E-mail: karimi@iasbs.ac.ir
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Publication History

Publication Date:
31 December 2001 (online)

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A variety of alcohols were acetylated in good to excellent yields with acetic anhydride in the presence of a catalytic N-bromosuccinimide (NBS) in CH2Cl2 and at room temperature. The reactions are clean and almost in all cases no detectable byproduct were observed.

acetates - N-bromosuccinimide - acetic anhydride - acetylation - acylation

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