Download PDF
Synlett 2001; 2001(4): 0547-0549
DOI: 10.1055/s-2001-12315
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Tetrabutylammonium Butyldifluorodimethylsilicate and Difluorodimethylphenylsilicate, New Nucleophilic Fluorinating Reagents

Jaroslav Kvíčala* , Petr Mysík, Oldřich Paleta
  • *Department of Organic Chemistry, Institute of Chemical Technology Prague, Technická 5, 166 28 Prague 6, Czech Republic; Fax + 420 2 2435 4288; E-mail: kvicalaj@vscht.cz
Further Information

Publication History

Publication Date:
31 December 2001 (online)

  PDF Download  Permissions and Reprints All articles of this category

Tetrabutylammonium butyldifluorodimethylsilicate (TAMBS, 1 a) and tetrabutylammonium difluorodimethylphenylsilicate (TAMPS, 1 b) were conveniently prepared from the corresponding substituted fluorodimethylsilanes and tetrabutylammonium fluoride. Both fluorosilicates 1 a, 1 b are powerful nucleophilic fluorinating reagents which transform primary or secondary halides, tosylates, or mesylates to the corresponding fluorides in moderate to good yields.

nucleophilic fluorination - hypervalent silicon compounds - butyldifluorodimethylsilicate - difluorodimethylphenylsilicate

      >