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Synlett 2001; 2001(2): 0257-0259
DOI: 10.1055/s-2001-10769
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A Rapid Synthesis of Racemic Brevioxime

Philip J. Parsons* , Burhan Karadogan, Jacqueline A. Macritchie
  • *The Chemical Laboratories, School of Chemistry, Physics & Environmental Science, University of Sussex, Falmer, Brighton, BN1 9QJ, UK; Fax +44 1273 677196; E-mail: P.J.Parsons§sussex.ac.uk
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Publication History

Publication Date:
31 December 2001 (online)

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Racemic brevioxime has been synthesised starting from N-propionyl-2-pyrroline by intramolecular cyclisation of a β-ketoamide using nitrosyl chloride.

brevioxime - β-ketoamide - N-propionyl-2-pyrroline - nitrosyl chloride

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