Synthesis 2000; 2000(11): 1532-1534
DOI: 10.1055/s-2000-7613
short paper
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Aromatization of Hantzsch 1,4-Dihydropyridines with I2-MeOH

Jhillu S. Yadav* , Basi V. Subba Reddy, Gowravaram Sabitha, Garudammagari S. Kiran Kumar Reddy
  • *Organic Chemistry Division-I, Indian Institute of Chemical Technology, Hyderabad-500 007, India
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Publication History

Publication Date:
31 December 2000 (online)

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4-Alkyl or aryl substituted Hantzsch 1,4-dihydropyridines are aromatized to the corresponding pyridines in high yields by iodine in refluxing methanol. The method tolerates several substituents such as alkyl, benzyl, aryl and heterocyclic groups present in the 4-position of pyridines.

Hantzsch 1,4-dihydropyridines - iodine-MeOH - aromatization

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