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Synthesis 1999; 1999(3): 479-482
DOI: 10.1055/s-1999-3408
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Transformations of Alkyl 2-(2,2-Disubstituted-ethenyl)amino-3-dimethylaminoprop-2-enoates: Synthesis of Alkyl 3,4-Disubstituted- and Alkyl 1-Acyl-3,4-disubstituted Pyrrole-2-carboxylates

Lovro Selič* , Branko Stanovnik
  • *Faculty of Chemistry and Chemical Technology, University of Ljubljana, Aškerceva 5, 1000 Ljubljana, Slovenia; Fax +3 86(61)1 26 32 57; E-mail: branko.stanovnik@uni-lj.si
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Publication Date:
31 December 1999 (online)

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Alkyl 3,4-disubstituted pyrrole-2-carboxylates were obtained by cyclization of alkyl 2-(2,2-disubstituted-ethenyl)amino-3-(dimethylamino)prop-2-enoates in acidic media, while in the presence of acyl chlorides alkyl 1-acyl-3,4-disubstituted pyrrole-2-carboxylates were formed.

alkyl substituted pyrrole-2-carboxylates - alkyl 1-acyl substituted pyrrole-2-carboxylates - nitrogen heterocycles

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