Download PDF
Synthesis 1999; 1999(3): 495-499
DOI: 10.1055/s-1999-3404
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Grignard and Cerium Reagents of Pyrimidine Derivatives

Akihiko Shimura* , Atsuya Momotake, Hideo Togo, Masataka Yokoyama
  • *Department of Chemistry, Faculty of Science, and Graduate School of Science and Technology, Chiba University, Yayoi-cho 1-33, Inage-ku, Chiba City 263-8522, Japan; Fax +81(43)2 90 28 74; E-mail: yokoyama@scichem.c.chiba-u.ac.jp
Further Information

Publication History

Publication Date:
31 December 1999 (online)

  PDF Download  Permissions and Reprints All articles of this category

5-(Pyrimidinyl)magnesium and cerium chlorides were prepared via the halogen-metal exchange of 5-bromopyrimidine with ethylmagnesium chloride and a sequential treatment of butyllithium and cerium(III) chloride, respectively. In a similar way, 5-[2,4-di(tert-butoxy)pyrimidinyl]magnesium and cerium chlorides were prepared from the reaction of 5-bromo-2,4-di(tert-butoxy)-pyrimidine with ethylmagnesium chloride and butylcerium chloride, respectively.

Grignard reagents - cerium reagents - pyrimidines - uracil - pseudouridine

      >