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Synlett 1999; 1999(12): 1981-1983
DOI: 10.1055/s-1999-2983
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Kinetic Enzymatic Resolution of Cyclopropane Derivatives

Jörg Pietruszka* , Thorsten Wilhelm, Andreas Witt
  • *Institut für Organische Chemie, Universität Stuttgart, Pfaffenwaldring 55, D-70569 Stuttgart, Germany; Fax + 711 685 4269; E-mail: joerg.pietruszka@po.uni-stuttgart.de
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Publication Date:
31 December 1999 (online)

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The kinetic enzymatic resolution of cyclopropane acetates was systematically investigated utilizing 16 different hydrolases. Best results were obtained with hydrolyses in the presence of Candida antarctica B lipase.

enzymes - enantiomeric resolution - cyclopropanes - asymmetric synthesis - boron

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